Lecture 20: Zoonotic Disease of Southwest Flashcards

(62 cards)

1
Q

what exacerbates zoonotic diseases in AZ

A

diversity of wildlife, disparities across communities, extreme climate, varying topography, close proximity to international border

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2
Q

where does tularemia occur in world

A

north america, Europe, former soviet union, china and japan

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3
Q

Tularemia occurs year round but increases at what time of year

A

winter due to increased hunting/contact with rabbits

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4
Q

for children specifically when is tularemia more common

A

summer when ticks and fleas more abundant

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5
Q

tularemia is typically present as what in lab settings

A

primary pneumonia or typhoidal tularemia

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6
Q

3rd most common reported lab associated bacterial infection

A

tularemia

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7
Q

tularemia is usually found in areas above ___ ft

A

3000

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8
Q

tularemia causative agent

A

francisella tularensis, gram negative bacteria

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9
Q

what disease is considered a potential bioterrorism weapon

A

tularemia because airborne

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10
Q

incubation period for tularemia

A

1-14 days

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11
Q

is tularemia directly transmitted from person to person

A

no but drainage from tularemia lesions is potentially infectious

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12
Q

how long can flies and ticks remain infected with tularemia

A

flies-14 days
ticks-lifetime

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13
Q

what are symptoms of tularemia

A

fever, chills, headaches, diarrhea, muscle aches, joint pain, dry cough, and progressive weakness

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14
Q

how is tularemia clinically diagnosed

A

history of tick bite or exposure to mammalian host or exposure to contaminated water

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15
Q

what is a differential diagnosis to tularemia

A

plague

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16
Q

without treatment of tularemia what could happen

A

respiratory failure, shock, death

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17
Q

the symptoms of tularemia are dependent on

A

route of tranmission/infection

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18
Q

what is the most common clinical form of tularemia

A

uclerglandular

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19
Q

what is a sign of glandular form of tularemia

A

regional lymphadenopathy with no ulcer

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20
Q

what are the signs of oculoglandular form of tularemia

A

bacteria enter the eye when person butchering animal and results in conjunctivitis with preauricular lymphadenopathy

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21
Q

how do you contract oropharyngeal form of tularemia and what are the signs

A

eating or drinking contaminated food or water
signs: stomatitis, tonsilitis, and cervical lymphadenopathy

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22
Q

what is the most serious form of tularemia

A

pneumonic because can spread from breathing dust or aerosols

** this form used as bioterrorism weapon

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23
Q

what is a symptoms of pneumonic tularemia

A

primary pleuropulmonary disease

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24
Q

what form of tularemia presents as a febrile illness without early localizing signs and symptoms

A

typhoidal

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25
what are the type A tularemia resevoirs
rabbits or ticks
26
where are type A tularemia strains localized to
western U.S.
27
what are type B tularemia resevoirs
hares, rodents
28
what are some modes of transmission of tularemia
bite of arthropods, skin, conjunctival sac, oropharyngeal mucosa with contaminated water, blood, or tissue while handling infected carcass, handling insufficiently cooked meat, drinking contaminated water, inhalation of dust, contaminated pelts and paws of animals, bites from other animals that chewed on infected rabbit carcass
29
what is treatment for tularemia
antibiotics- gentamicin, doxycycline, ciprofloxacin
30
is tularemia a reportable disease
yes! must be reported to AZDA within 4 hours
31
how would you mail tularemia samples
Class B (unconfirmed)
32
how to prevent tularemia
insect repellent, tick protection, wash hands after handling animal carcasses, drink only treated water, note any change in behavior of your pets or livestock
33
what is the most severe disease caused by a tick in U.S.
RMSF
34
what % of cases of RMSF are fatal
5-10%
35
arizona has the most cases of what tickborne disease
RMSF
36
what is the causative agent for RMSF
Rickettsia Rickettsii- gram negative
37
what is incubation period of RMSF
2-14 days
38
R. Rickettsii invades what cells and causes what
invades endothelial cells of the venules and capillaries and begins replicating, causing vasculitis- why you get spots
39
what is common symptom of RMSF and why
rash/red dots from blood vessels leaking
40
what are some late stage clinical signs of RMSF
necrosis on extremities, altered mental status, polyarthritis, vestibular deficits, dyspnea, cough
41
what are the most common abnormal clinical lab signs of RMSF
hypoalbuminemia, moderate leukocytosis, thrombocytopenia
42
how do you diagnose RMSF
serologic test via IFA
43
treatment for RMSF
doxycycline
44
how to prevent RMSF
promptly remove ticks, tick preventatives, treat tick environments
45
who is the primary reservoir for chagas
dogs
46
how long does chagas infection last
lifelong
47
what is causative agent for chagas
protozoan parasite- trypanosoma cruzi
48
what is primary vector for chagas
triatomines- kissing bug feces of bug contain parasites
49
what are some other modes of transmission of chagas besides kissing bug
congenital- mother to fetus blood transfussion organ transplant contaminated foods, acai palm fruit, guava juice, juice prepared from sugarcane
50
control of chagas disease in U.S. is focused on what
non-vector borne methods
51
what are the two phases of chagas
acute and chronic
52
what are acute signs of chagas
fever, fatigue, body ache, rash, diarrhea, vomiting, swelling of eyelids
53
what are the chronic signs of chagas
cardiac or GI complications
54
which zoonotic disease can cause immunocompromised children to die from myocarditis or meningeoencephalitis
chagas
55
how to diagnosis chagas
acute phase: find trypomastigotes in blood or CSF chronic: serologic testing
56
how to treat chagas
antiparasitics- benzidazole and nifurtimox
57
what are some signs dogs with chagas disease present with
dilated cardiomyopathy
58
why are dog kennels with high density of dogs suitable environment for kissing bug
heat and CO2 attract kissing bug
59
how to prevent chagas
turning off outdoor lights, cleaning up brush, housing dogs insides, using insecticides
60
do traditional flea and tick repellents kill kissing bugs
no!
61
what organism is the onchocera lupi from
filarial nematode
62
how to diagnose onchocera
skin biopsy