Lecture 3 Western Countries II Flashcards

(51 cards)

1
Q

How many years was medicine plant based?

A

2,500 years

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2
Q

When did industrial pharmaceutical medicine emerge?

A

In last 100 years

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3
Q

Time analogy medicine

A

Natural med - 59 mins
Pharmaceutical - 1 min
of human history

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4
Q

Where did knowledge of TPM first originate

A

Persian and Egyptian Physicians

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5
Q

Graeco-Roman texts were translated by

A

Arabic physicians and reintroduced into Europe in Middle Ages and Renaissance

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6
Q

Knowledge was passed down formally and informally by who

A

Physicians and pharmacists formally and informally in households

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7
Q

What % of the world’s pop uses traditional medicine?

A

5.6 billion

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8
Q

WHO strategy to be extended to 2025

A

o Promote co-existence of traditional and pharmaceutical medicine.
o Best patient outcomes when both systems are integrated.

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9
Q

Key Principles of WHM: Holistic and Vitalistic:

A

o Treat the root cause, not just symptoms.
o Address physical, mental, emotional well-being.
o Body has a self-healing “vital force” (homeostasis).

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10
Q

Key Principles of WHM: * Empirical Basis

A

o Based on centuries of clinical observation (repeatable, verifiable)
o Not based on theory, but on results in real-life patients.

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11
Q

Key Principles of WHM, * Core Treatment Strategy:
Combine plant-based medicine with…

A

 Healthy diet
 Healthy lifestyle
 Psychosocial wellness

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12
Q

WHM is practiced where

A

Europe (UK, Russia), USA, Canada, Australia, NZ (NZQA approved), South Africa.

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13
Q

Europe WHM called

A

Traditional European Medicine (TEM), Phytotherapy.

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14
Q

Plant source: how many species

A

o ~350 main plant species.

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15
Q

What are the plant sources

A

Mostly European flora + Middle Eastern spices (e.g. saffron, cinnamon) + New World plants post-15th century (e.g., cinchona bark).

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16
Q

What are the formulations of Western Herbal Medicine

A

Infusions, decoctions, tinctures, fluid extracts, essential oils, syrups, pastilles, creams, inhalations, etc.

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17
Q

Traditional Plant Medicine

A

Medicines made from whole plants or plant parts, following long-standing customs. Usually used in combinations rather than as single herbs.

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18
Q

TPMs vs supplements

A

TPMs are pharmacologically active and affect organ function where as supplements provide nutrition and don’t impact disease directly

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19
Q

WHM is effectively what type of trial

A

2500 year long clinical trial

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20
Q

Over time the dosage and formulations have been

A

evolved to maximise the effect and minimise harm

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21
Q

What % of the top 119 drugs are based on or derived from traditional medicinal plants

23
Q

What are Natural Products?

A

Substances derived from plants, animals, fungi, or microorganisms.

24
Q

Define Phytochemicals.

A

Bioactive plant chemicals responsible for therapeutic effects.

25
What are Secondary Metabolites?
Non-essential for plant survival, but important for defence and interaction (e.g. alkaloids, phenolics, terpenoids).
26
What is Phyto-therapy?
Plant-based therapy.
27
Define Phytopharmacy.
The study and application of whole herbal extracts as therapeutic agents.
28
What does WHM stand for?
Western Herbal Medicine.
29
WHM is likened to which role in healthcare?
Gardener.
30
What is the role of Western Drug Medicine?
Targets and eliminates disease symptoms.
31
What is a focus of WHM?
* Prevention of illness * Treatment of chronic, non-life-threatening ailments * Enhancing overall health and resilience.
32
Why do patients prefer WHM?
For its perceived safety, tradition, and holistic approach.
33
What are Traditional Plant Medicines (TPMs) recognized as?
Essential medicines for achieving Universal Health Coverage.
34
List three gaps where TPMs address healthcare needs.
* Pharmaceuticals are ineffective or inappropriate * Side effects from synthetic drugs need to be mitigated * Chronic or functional diseases persist.
35
What is a holistic assessment in WHM?
Looks at the whole person, not just symptoms.
36
What does individualised treatment in WHM refer to?
Customised based on patient history and constitution.
37
What are the three types of causes in the multifactorial understanding of disease?
* Predisposing causes (e.g. genetics) * Precipitating causes (e.g. pathogens) * Perpetuating causes (e.g. chronic stress, environmental factors).
38
What is the primary distinction between whole plant extracts and isolated compounds?
The whole extract is the drug, not a single isolated compound.
39
Provide an example of a whole extract and its isolated compound.
St John’s Wort ≠ hypericin or hyperforin.
40
In which regions are whole extracts recognized as herbal medicines?
EU and Switzerland.
41
What does synergy in TPMs refer to?
Combined effect of multiple constituents > sum of individual effects.
42
Give an example of a plant extract with synergy.
Thymus vulgaris (thyme) whole extract more effective than synthetic thymol.
43
What are the benefits of whole extracts in plant medicines?
* Specific effects (e.g. calming nerves) * Multi-target (pleiotropic) effects (e.g. sleep + pain relief) * Broad-spectrum (e.g. immune support, anti-inflammatory).
44
Why are plants considered generally safer than synthetic drugs?
* Mild receptor activity * Evolutionary kinship with humans = high compatibility * Low side effects at therapeutic doses.
45
What should scientific safety assessments focus on?
Whole extracts, not isolates.
46
What are the therapeutic effects of St. John’s Wort?
* Antidepressant: inhibits reuptake of serotonin, dopamine, noradrenaline * Anxiolytic: activates benzodiazepine receptors * Neuroprotective and adaptogenic * Anti-inflammatory, analgesic, digestive tonic.
47
How does the safety profile of St. John’s Wort compare to SSRIs?
Low side-effect profile compared to SSRIs/tricyclics.
48
What is the ideal use for WHM?
Chronic, functional illness.
49
What is the ideal use for Conventional Medicine?
Emergencies, acute conditions.
50
True or False: WHM is targeted and symptomatic.
False.
51
What is the quote regarding good medicine?
"Good medicine is about doing right for the patient."