Lecture 5- Adaptive Immune System Flashcards
How do host cell identify viruses?
MHC
Which MHC class is on most nucleated cells
MHC I
What kind of particles does MHC present
Viral particles and self-antigens
Which MHC class is on immune cells
MHC II
Types of antibody-mediated immune cells
B cells
plasma cells
Types of cell-mediated immune cells
Cytotoxic T cells
Regulatory T cells
Where are antigens presented to lymphcytes
lymphoid organs
what are the roles of a lymphoid organ
- regulate production of lymphocytes
Provide an environment for trapping and processing foreign antigens - maximize the opportunity for lymphocytesand antigens to come into contact
Examples of primary lymphoid organs and what they do
Thymus, bursa, peyer’s patches, marrow
Produce T and B cells
Examples of secondary lymphoid organs and what they do
tonsils, spleen, lymph nodes, marrow, peyer’s patches
where lymphocytes respond to and encounter antigens
Where are T cells primarily produced
thymus
Where are B cells primarily produced
bursa-birds
marrow- primates and rodents
intestines (peyer’s patches)- ruminants
Purpose of lymph nodes
Filter lymphatic fluid
Antigen-lymphocyte interaction
Purpose of the spleen
Filter antigens out of blood
Which cells are the first to interact to a vaccine injected SQ
Langerhans and classical dendritic cells, then neutrophils will migrate out of the blood
