Lecture Quiz 6 Flashcards

(43 cards)

1
Q

Where is the heart located?

A
in the mediastinum
superior to the diaphragm
anterior to the vertebral column
posterior to the sternum
left to the midline
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2
Q

What is the pericardium?

A

a double walled sac around the heart

composed of a superficial fibrous pericardium and deep two-layer serous pericardium

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3
Q

What is the parietal layer?

A

pericardium

lines the internal surface of the fibrous pericardium

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4
Q

What is the visceral layer of the pericardium?

A

epicardium

lines the surface of the heart

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5
Q

How are the layers of the pericardium separated?

A

a fluid-filled pericardial cavity

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6
Q

What does the pericardium do?

A

protects and anchors the heart
prevents overfilling of the heart with blood
allows the heart to work in a friction-free environment

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7
Q

What are the layers of the heart wall?

A

epicardium
myocardium
endocardium

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8
Q

What is the epicardium?

A

visceral layer of the serous pericardium

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9
Q

What is the myocardium?

A

cardiac muscle layer forming the bulk of the heart

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10
Q

What is the endocardium?

A

endothelial layer of the inner myocardial surface

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11
Q

What are the atria?

A

the receiving chambers of the heart

each atrium has a protruding auricle

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12
Q

What are the pectinate muscles?

A

mark atrial walls

help atria contract more efficiently

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13
Q

What are the ventricles?

A

the discharging chambers of the heart

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14
Q

What are the papillary muscles?

A

line ventricular walls

prevent blood flowing back into atria

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15
Q

What are the trabeculae carnae muscles?

A

mark ventricular walls

make contraction more efficient

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16
Q

What difference do you find between the right and left ventricle?

A

both hold the same volume of blood, but the left ventricular wall is thicker

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17
Q

Of the four chambers, how do they relate in chamber size?

A

atria are smaller than the ventricles

right side = left side

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18
Q

Of the four chambers, how do they differ in wall thickness?

A

atria < ventricles

right ventricle < left ventricle

19
Q

What percentage do the atria account for blood pumped?

A

at rest, 5%

exercise, 40%

20
Q

What are the atrioventricular valves of the heart (general)?

A

valves between the atria and ventricles

prevent backflow into the atria when the ventricles contract

21
Q

What are the chordae tendineae?

A

anchor atriventricular valves to papillary muscles

22
Q

What is the mitral (bicuspid) valve?

A

AV valve between left atrium and left ventricle

23
Q

What is the tricuspid valve?

A

AV valve found between the right atrium and right ventricle

24
Q

What are the semilunar valves?

A

lie between the ventricle and the aorta

prevent the backflow of blood into the ventricles

25
What is the aortic valve?
semilunar valve leading from the left ventricle into the aorta
26
What is the pulmonary valve?
lies between the right ventricle and the pulmonary trunk
27
What are arteries?
vessels that take blood away from the heart
28
What are veins?
vessels that return vlood to the heart
29
Where does oxygenation of blood occur?
varies in arteries and veins
30
What does pulmonary circulation do?
enriches the blood with oxygen and removes excessive carbon dioxide
31
Describe the pathway of the pulmonary circulation
blood enters right ventricle through tricuspid valve passes through pulmonary valve to pulmonary trunk splits into left and right pulmonary arteries travels through capillaries of the lungs for gas exchange right and left pulmonary veins return blood to left atrium
32
What does systemic circulation do?
carries oxygenated blood to the entire body
33
Describe the pathway of systemic circulation
blood passes through mitral valve into left ventricle travels through aortic valve into aorta and its branches capillaries in peripheral tissues allow gas exchange blood is returned to the right atrium through the superior and inferior venae cavae and the coronary sinus
34
What are cardiomyocytes?
large, branched cells single central nucleus striated heavily vascularized
35
What do intercalated discs of cardiac cells do?
connect cardiomyocytes allow free passage of ions between the cells allows heart muscle to contract simultaneously as a functional system
36
How is the heart stimulated and what is that known as?
by nerves also self-excitable this is known as automaticity
37
What are the two types of cardiomyocytes?
contractile cells | pacemaker cells
38
What happens during phase 0 of action potential in contractile cardiomyocytes?
slow sodium channels leak until the muscle reaches the threshold of the fast sodium channels sodium ions rush in until the membrane polarity is reversed
39
What happens during phase 1 of action potential in contractile cardiomyocytes?
polarity reversal causes the fast sodium channels to snap shut and the potassium channels to open this causes the membrane potential to start to become more negative
40
What happens during phase 2 of action potential in contractile cardiomyocytes?
plateau potassium ions continue leaking out calcium channels open and positively charged calcium ions leak in, cancelling the effect of potassium ions leaking out no net change for 100 milliseconds calcium ions are used to form cross bridges excitation-contraction coupling: calcium ions cause the plateau phase and bind to troponin and initiate cross bridge formation
41
What happens during phase 3 of action potential in contractile cardiomyocytes?
repolarization calcium ions quit leaking in passage of potassium ions out of the cell causes a return to the resting membrane potential
42
What happens during phase 4 of action potential in contractile cardiomyocytes?
resting potential | the only activity during this phase is the constant leakage of the slow sodium channels
43
What is unique about the refractory period in cardiomyocytes?
it is very long ~250 msec | premature stimulation does not cause tetanus for this reason