Lecturer: Hemostasis Flashcards Preview

AP: Cumulative > Lecturer: Hemostasis > Flashcards

Flashcards in Lecturer: Hemostasis Deck (14)
Loading flashcards...
1
Q

KEY TERM

Three phases of hemostasis:

A

primary: formation of platelet plug
secondary: coagulation

tertiary: fibrinolysis

2
Q

What is von Willebrand factor? (2)

A

protects factor 8 from rapid inactivation

binds platelets

3
Q

KEY TERM

What is the most common congenital bleeding disorder?

A

Von Willebrand’s disease

4
Q

Most comon agonists for platelet activation: (3)

A

collagen

thrombin

epinephrine

5
Q

What are the primary adhesive molecules? (2)

A

fibrinogen

vWF

6
Q

What is the fibrin stabilizing factor?

A

8

7
Q

What are vitamin K dependent factors? (4)

A

2

7

9

10

8
Q

Deficiency of factor 8 results in:

A

hemophilia A

9
Q

Deficiency of factor 9 results in:

A

hemophilia B

10
Q

Neonates have a well balanced, efficient hemostatic system. True or false?

A

true

11
Q

Fetal form of fibrinogen exists until ___ year of age.

A

1

12
Q

Fibrin clot of neonates are less dense. True or false?

A

true

13
Q

Off label use of factor 7:

A

post-cardiopulmonary bypass

14
Q

What model provides an in vivo model of the coagulation process?

A

Cell-based model