Lecturer: Hemostasis Flashcards Preview

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Flashcards in Lecturer: Hemostasis Deck (14):
1

KEY TERM

Three phases of hemostasis:

primary: formation of platelet plug

secondary: coagulation

tertiary: fibrinolysis

2

What is von Willebrand factor? (2)

protects factor 8 from rapid inactivation

binds platelets

3

KEY TERM

What is the most common congenital bleeding disorder?

Von Willebrand's disease

4

Most comon agonists for platelet activation: (3)

collagen

thrombin

epinephrine

5

What are the primary adhesive molecules? (2)

fibrinogen

vWF

6

What is the fibrin stabilizing factor?

8

7

What are vitamin K  dependent factors? (4)

2

7

9

10

8

Deficiency of factor 8 results in:

hemophilia A

9

Deficiency of factor 9 results in:

hemophilia B

10

Neonates have a well balanced, efficient hemostatic system.  True or false?

true

11

Fetal form of fibrinogen exists until ___ year of age.

1

12

Fibrin clot of neonates are less dense.  True or false?

true

13

Off label use of factor 7:

post-cardiopulmonary bypass

14

What model provides an in vivo model of the coagulation process?

Cell-based model