Flashcards in LG4.3 Arthritis II – Winfield Deck (29):
What are general characteristics of reactive arthritis?
What are the symptoms of reactive arthritis?
-Rash on hands, feet, penis.
What is the classic triad of reactive arthritis?
Arthritis, conjunctivitis, urethritis
What are the general symptoms of ankylosing spondylitis?
-persistent low back pain in teenager or early 20's
-Spinal fusion with stooped posture and loss of spinal mobility
A painful condition of the spine resulting from the degeneration of the intervertebral disks.
What are the main characteristics of ankylosing spondylitis?
-In lumbar spine, hips, pelvis, eye
What are the main genetic predisposition of ankylosing spondylitis?
Class 1: HLA-B27
What are the general characteristics of Enteropathic arthritis?
-20% of IBD develop a peripheral arthritis
-course of arthritis often fluctuates with the activity of the underlying bowel involvement.
-10-20% spinal involvement
What are extra-articular manifestations of enteropathic arthritis?
Inflammatory eye disease and cutaneous lesions
What is the problem in psoriasis?
-The skin grows to quickly forming skin lesions.
-Nail discolorations and pitting
-can develop arthritis
What is the cause of psoriasis?
T-cell mediated disease with a genetic basis
Who gets psoriasis?
What is the general characteristics of Psoriatic arthritis?
-Skin lesions and nail discoloration
-caused by psoriasis
What does it mean for a diseases to be Seronegitive spondyloarthropathies?
-No RF and ACPA values
What is Inflammatory bowel disease?
Diseases that cause chronic recurrent inflammation of the intestines
What are the causes of inflammatory bowel disease?
-Genetic family risk
-Caucasians have higher risk
-Jew have higher risk
-Ages 10-30 and 50-60
What are the symptoms of inflammatory bowel disease?
Abdominal cramps and pain, diarrhea, weight loss, and hematochezia
What are the clinical presentation of Rheumatoid Arthritis?
-Joint tenderness and swelling
-Morning joint stiffness for an hour or more
-Progressive joint destruction
What are extra-articular manifestations of Rheumatoid Arthritis?
-Scleritis, pericarditis, conduction defects, lung nodules, pulmonary fibrosis, gastritis, peptic ulcer disease 2nd to NSAIDS.
What is the cause of Rheumatoid Arthritis?
-Possible infectious agent
What are risk factors of Rheumatoid Arthritis?
-Female 3:1 male
-onset at any age, most common 40-50
What are lab test for Rheumatoid Arthritis?
-Anti-cyclic cirtullinated peptide(ACCP)
What are the non-pharmacologic treatments for Rheumatoid Arthritis?
-Range of motion exercises
What are pharmacologic treatments for Rheumatoid Arthritis?
-Disease Modifying Antirheumatic Drugs (DMARD)
-Oral Hydroxychloroquine, Sulfasalazine, and Methotrexate
What are the clinical presentation of erosive inflammatory osteoarthritis?
-Typical OA has enlargement of bones over the distal and proximal finger joints.
-Swelling of the soft tissue in the proximal and distal interphalangeal joints.
What are common labs for erosive inflammatory osteoarthritis?
-RF/ACCP are negative
-ESR and CRP increased
What are the treatments of erosive inflammatory osteoarthritis?
-PRN pain meds and no steroidal anti-inflammatory drugs for symptom relief
What are main lab values for septic arthritis?
-Lab: Synovial WBC >100,000 PMNs are 90% or above