Flashcards in LG4.6 Pathology: Gout – Dr. Fischione Deck (11):
What are the general characteristics of Gout?
-Deposition of uric acid crystals
-Primarily joints, subcutaneous tissues, kidneys
Who is most at risk for Gout?
-Alcohol use (Beer, liquor, wine)
What are the cystals in Gout made of?
Symptoms of Acute Gout?
-Hyperemic, swollen, and warm
-Fever, leukocytosis, tachycardia, and general exhaustion
Symptoms of Chronic Gout?
-More bone deformities (Mouth eaten bones)
What and where is Tophi at?
-Often presents with subcutaneous deposits of uric acid
-Most often found on ears, the extensor sites of the arms, over the olecranon, and the patella
What are the characteristic of Pseudogout?
-Old age with those over 85 y/o
-2/3 have previous joint damage.
-IN THE KNEES
What are the characteristics of the crystals of pseudo gout?
Short, stubby, and rhomboid
What substance is in excess in Pseudogout?
-Inorganic pyrophosphate in the synovial fluid.
-Deposition of Calciu pyrophosphate in knees after trauma.
In gout where do most crystals deposit?
In the kidneys