LG4.6 Pathology: Gout – Dr. Fischione Flashcards Preview

NMSK A Test 2 > LG4.6 Pathology: Gout – Dr. Fischione > Flashcards

Flashcards in LG4.6 Pathology: Gout – Dr. Fischione Deck (11):
1

What are the general characteristics of Gout?

-Hyperuricemia
-Deposition of uric acid crystals
-Primarily joints, subcutaneous tissues, kidneys

2

Who is most at risk for Gout?

-Men (95%)
-Alcohol use (Beer, liquor, wine)

3

What are the cystals in Gout made of?

Monosodium Urate

4

Symptoms of Acute Gout?

-Hyperemic, swollen, and warm
-Cannot walk
-Fever, leukocytosis, tachycardia, and general exhaustion

5

Symptoms of Chronic Gout?

-Less inflammation
-More bone deformities (Mouth eaten bones)
-Tophi

6

What and where is Tophi at?

-Often presents with subcutaneous deposits of uric acid
-Most often found on ears, the extensor sites of the arms, over the olecranon, and the patella

7

What are the characteristic of Pseudogout?

-Old age with those over 85 y/o
-2/3 have previous joint damage.
-IN THE KNEES

8

What are the characteristics of the crystals of pseudo gout?

Short, stubby, and rhomboid

9

What substance is in excess in Pseudogout?

-Inorganic pyrophosphate in the synovial fluid.
-Deposition of Calciu pyrophosphate in knees after trauma.

10

In gout where do most crystals deposit?

In the kidneys

11

What is podagra?

-1st symptom of Gout
-Gout of the foot
-Causes seizure of the foot