Lipid pathways Flashcards

(58 cards)

1
Q

Name the pathway

A

Beta-oxidation

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2
Q

Process 1

  • Enzyme
  • Reactions
A

Acyl-CoA dehydrogenase

  • FAD → FADH2
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3
Q

Compound A

  • Name
  • Structure
A

Fatty acyl-CoA

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4
Q

Compound B

  • Name
  • Structure
A

trans-enoyl-CoA

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5
Q

Process 2

  • Enzyme
  • Reactions
A

Enoyl-CoA hydratase

  • H2O →
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6
Q

Compound C

  • Name
  • Structure
A

β-hydroxyacyl-CoA

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7
Q

Process 3

  • Enzyme
  • Reactions
A

β-hydroxyacyl-CoA dehydrogenase

  • NAD+ → NADH + H+
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8
Q

Compound D

  • Name
  • Structure
A

β-ketoacyl CoA

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9
Q

Process 4

  • Enzyme
  • Reactions
A

Thiolase

  • CoA-SH →
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10
Q

Compound E

  • Name
  • Structure
A

Acetyl-CoA

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11
Q

Process 1

  • Enzymes
  • Reactions
A

Propionyl-CoA carboxylase

  • HCO3-
  • ATP → ADP + P<span>i</span>
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12
Q

Give the structure of Propionyl-CoA

A
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13
Q

Compound B

  • Name
  • Structure
A

D-Methylmalonyl-CoA

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14
Q

Process 2

  • Enzyme
  • Reactions
A

Methylmalonyl-CoA epimerase

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15
Q

Compound C

  • Name
  • Structure
A

L-Methylmalonyl-CoA

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16
Q

Process 3

  • Enzyme
  • Reactions
A

Methyl-malonyl-CoA mutase

With coenzyme B12

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17
Q

Compound D

  • Name
  • Structure
A

Succinyl-CoA

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18
Q

Name the pathway

A

Ketogenesis

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19
Q

Compounds A + B

  • Name
  • Structure
A

2 x Acetyl-CoA

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20
Q

Process 1

  • Enzyme
  • Reactions
A

Thiolase

  • → Acetoacetyl-CoA
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21
Q

Compound C

  • Name
  • Structure
A

Acetoacetyl-CoA

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22
Q

Process 2

  • Enzyme
  • Reactions
A

HMG-CoA synthase

  • Acetyl-CoA → CoA-SH
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23
Q

Compound D

  • Name
  • Structure
A

HMG-CoA

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24
Q

Process 3

  • Enzyme
  • Reactions
A

HMG-CoA lyase

  • → CoA-SH
25
Compound E * Name * Structure
Acetoacetate
26
Process 4 * Enzyme * Reactions
Non-enzymatic decarboxylation * → CO2
27
Compound F * Name * Structure
Acetone
28
Process 5 * Enzyme * Reactions
D-β-hydroxybutyrate dehydrogenase * NADH + H+
29
Compound G * Name * Structure
D-β-hydroxybutyrate
30
Compound A * Name * Structure
D-β-hydroxybutyrate
31
Process 1 * Enzyme * Reactions
D-β-hydroxybutyrate dehydrogenase * NAD+ → NADH
32
Compound B * Name * Structure
Acetoacetate
33
Process 2 * Enzyme * Reactions
SCOT * Succinyl-CoA → Succinate
34
Compound C * Name * Structure
Acetoacetyl-CoA
35
Process 3 * Enzyme * Reactions
β-ketothiolase * CoA-SH →
36
Compound D * Name * Structure
Acetyl-CoA
37
Process 4 * Enzyme * Reactions
Citrate Synthase
38
Name the pathway
Fatty acid synthesis
39
Compound A (A) * Name * Structure
Acetyl-ACP
40
Compound B (M) * Name * Structure
Malonyl-ACP
41
Process 1 * Enzyme * Reactions
* Condensation* * → ACP + CO2
42
Compound C * Name * Structure
β-ketoacyl-ACP
43
Process 2 * Enzyme * Reactions
Keto group reduction * NADPH → NADP+
44
Compound D * Name * Structure
β-hydroxyacyl-ACP
45
Process 3 * Enzyme * Reactions
* Dehydration* * → H2O
46
Compound E * Name * Structure
*trans*-2-enoyl-ACP
47
Process 4 * Enzyme * Reactions
* Enoyl reduction* * NADPH → NADP+
48
Compound F * Name * Structure
Acyl-ACP
49
Compound A * Name * Structure
Glycerol-3-phosphate
50
Process 1 * Enzyme * Reactions
GPAT * FA-CoA → CoA-SH
51
Compound B * Name * Structure
Monoacylglycerol-P
52
Name the pathway
Fat (TAG) synthesis
53
Process 2 * Enzyme * Reactions
AGPAT * FA-CoA → CoA-SH
54
Compound C * Name * Structure
Phosphatidic acid
55
Process 3 * Enzyme * Reactions
PAP * H2O → Pi
56
Compound D * Name * Structure
Diacylglycerol
57
Process 4 * Enzyme * Reactions
DGAT * FA-CoA → CoA-SH
58
Compound E * Name * Structure
Triacylglycerol