Liver Disorders Flashcards

(51 cards)

1
Q

Main causes of hepatits

A

alcohol
acetaminophen
EBV

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2
Q

Acute Viral Hepatits

A

increase of LFTs and jaundice

IgM

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3
Q

Chronic Viral Hepatitis

A

virus not cleared by immune system
asymptomatic
increased LFT
IgG

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4
Q

Tests for Liver Damage

A

ALT (best)

AST (muscles)

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5
Q

Tests for Liver Function

A

ALP (bone)

GGT (shows alcoholism)

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6
Q

Viral Hepatitis

A

kills hepatocytes

all liver tests high

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7
Q

Primary Hepatitis

A

Hepatocytes rupture

increased ALT and AST

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8
Q

Secondary Hepatitis

A

lever swells,and damages canals

increased ALP, GGT, bilirubin

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9
Q

Primary Bile Duct Block

A

prevents bilirubin excretion and damages canalicular cells

increased bili, ALP, GGT

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10
Q

Secondary Bile Duct Block

A

minor damage to hepatocytes

increased ALT and AST

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11
Q

Hepatitis A and E are transferred by…

A

fecal- oral

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12
Q

Complications of HAV and HEV

A

acute and self limiting

no carrier status

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13
Q

Hepatitis B route of transmission

A

blood borne

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14
Q

Hepatitis D needs _____ to infect

A

Hep B

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15
Q

20% Viral Hepatitis Rule

A

20% of chronic hepatitis progresses to cirrhosis

20% of cirrhosis progresses to hepatocarcinoma

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16
Q

HBV Carriers will not contain….

A

anti-HBs antigen

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17
Q

Types of hepatitis caused by Hep B

A

fulminant hepatitis
chronic hepatits
chances increased with Hep D

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18
Q

Ig for acute HBV

A

IgM

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19
Q

Ig for chronic HBV

A

IgG

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20
Q

Vaccine for HBV

A

HBsAg

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21
Q

Presence of anti-surface antibodies indicates….

A

patient already vaccinated

22
Q

Presence of anti-core antibodies indicates….

A

patient already had virus

23
Q

Transmission of Hepatitis C

A

high chance from blood/ needles

low chance from sex and mother/infant

24
Q

Symptoms of Hep C

A

most are asymptomatic and chronic carriers

25
#1 and 2 causes of chronic hepatitis, cirrhosis, liver cancer
Hep C | Hep B
26
Vaccine for Hep C
there isnt one
27
HCV more responsive to seroconversion
HCV-2
28
Hemochromatosis
iron overload in body
29
Needed for PT/INR
coumadin
30
Cirrhosis
end of chronic liver disease- replaces w/ fibrous tissue | jaundice and ascites
31
Causes of Cirrhosis
EBV alcohol acetaminophen
32
Complications of Cirrhosis
portal hypertension GI bleeding liver failure
33
Jaundice is noticed first in....
sclera
34
Cause of Jaundice
increased blood bilirubin
35
Wilson's Disease is a mutation of....
ATP7P
36
Wilson's Disease
copper transport problem | accumulates in liver, brain, eyes
37
Kayser-Fleischer Ring
copper build up in Descemet's | Wilson's Disease
38
Sunflower Cataracts
copper in anterior and posterior capsule | Wilson's Disease
39
Diagnosing Wilson's Disease
low serum ceruplasmin | high copper excretion
40
Treating Wilson's Disease
copper removal chelating agents block copper absorption with zinc salts
41
Hemachromatosis
Iron overload- increased absorption
42
Signs of Hemachromatosis
bronzed skin
43
Diagnosing Hemachromatosis
high serum iron and ferritin
44
Treating Hemachromatosis
phlebotomy
45
Cholelithiasis
gallstones
46
Cholecystitis
inflammation of gallbladder
47
Cholangitis
inflammation of common bile ducts
48
Symptoms of Cholecystitis
RUQ pain worsened by fatty acids | Murphy's Sign
49
Lab Results of Cholecystitis
AST/ ALT mildly elevated
50
Pancreatitis
secondary to acohol abuse or gallstones
51
Lab Results of Pancreatitis
serum amylase and lipase