Lower respiratory tract infections Flashcards

(45 cards)

1
Q

What is examples of lower respiratory tract infections

A
Acute bronchitis
Exacerbation of COPD
Pneumonia
Empyema
Lung Abscess
Bronchiectasis
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2
Q

What is the symptoms of pneumonia

A
Malaise - tirdness 
Fever
Chest pain (pleuritic) - painful when breath 
Cough
Purulent sputum
Dyspnoea - breathlessness
Headache
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3
Q

What is the sputum produced in pneumonia caused by Streptococcus pneumoniae and Klebsiella pneumoniae called

A

rusty sputum

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4
Q

What is the signs of pneumonia

A
Pyrexia
Tachpnoea - fast respiratory rate 
Central cyanosis (blue tongue)
Dullness on percussion of affected lobe(s)
Bronchial breath sounds - harsh 
Inspiratory crepitations (rattes)
Increased vocal resonance
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5
Q

What does the sign of central cyanosis indicate on a patient with pneumonia

A

Patient has become hypoxic

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6
Q

What is the different investigations used for pneumonia

A
Serum biochemistry and full blood count
Chest X-Ray (CxR)
Blood cultures
Throat swab (for atypical pathogens)
Urinary legionella antigen
Sputum microscopy and culture
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7
Q

Why does a chest X-ray look white for a patient with pneumonia

A

looks white as alveoli filled with bacterial cells and inflammatory substances

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8
Q

Why are blood tests and sputum culture important in investigation of pneumonia

A

used to confirm an infection and to try to identify the type of organism causing the infection

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9
Q

What is the purpose of the Urinary legionella antigen investigation

A

To test for Legionnaires’ disease which is a form of atypical pneumonia caused by any type of Legionella bacteria

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10
Q

What is the greatest causing pathogens of pneumonia

A
Strep Pneumoniae				36%
H. Influenzae					10.2%
Legionella					0.4%
Staph aureus					0.8%
Mycoplasma pneumoniae		1.3%
Chlamydia psittaci				1.3%
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11
Q

What are the risk factos affect the scoring on your severity of pneumonia

A
The CURB 65 
C		confusion
U	        blood urea>7
R		respiratory rate>30
B		diastolic blood pressure<60
65	         age>65
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12
Q

If you have 0 of the CURB 65 risk factors what is your severity and antibiotic treatment

A

low risk and could be treated in community with Amoxycillin or clarithromycin / doxycycline

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13
Q

If you have 1-2 of the CURB 65 risk factors what is your severity
if you have CURB2 how many antibiotics must you take and what are there names

A

hospital treatment usually required

2 -Amoxycillin and clarithromycin

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14
Q

If you have 3-5 of the CURB 65 risk factors what is your severity and antibiotic treatment

A

high risk of death and need for ITU

Co-amoxiclav and clarithromycin

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15
Q

When would levofloxacin be given in the treatment of pneumonia

A

CURB2 and above if patient is allergic to penicillin

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16
Q

What is the non antibiotic treatment for pneumonia

A

Oxygen
i.v. fluids
CPAP - continued positive airway pressure
Intubation and ventilation - if severe

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17
Q

What is continued positive airway pressure

A

a form of positive airway pressure ventilator, which applies mild air pressure on a continuous basis to keep the airways continuously open in people who aren’t able to breathe spontaneously on their own

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18
Q

What is the complications of pneumonia

A
Septicaemia - infection in blood 
Acute Kidney Injury
Empyema
Lung Abscess
Haemolytic anaemia (breakdown of RBC)
Acute respiratory distress syndrome
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19
Q

What different diagnosis can be made instead of pneumonia

A
Tuberculosis
Lung cancer
Pulmonary embolism
Cardiac failure
Pulmonary vasculitis (Wegners granulomatosis)
20
Q

If the symptoms carry on for a long time is it more likely to be pneumonia or TB

21
Q

What could be mistaken as pneumonia on an X-ray

A

pulmonary embolism

pulmonary vasculitis

22
Q

What further condtions could follow pneumonia

A

Lung abscess
empyema
(bronchiectasis)

23
Q

What pathogens are responsible for empyema

A

Streptococcus (52%),
Staph. Aureus (11%),
Anaerobes (20%)

24
Q

What is empyema

A

collection of pus (infection) in the pleural cavity

25
What is the symptoms of empyema
Chest pain High swimming fever (no cough)
26
What is used to investigate and diagnose a empyema
investigate - CT thorax and pleural ultrasound | Diagnose - pleural aspiration
27
What pH of the pleural aspiration of a patient with empyema
< pH 7.2
28
What is the treatment for empyema
Treatment is chest drain and intravenous antibiotics (antibiotics up to 6 weeks) surgery if don't respond
29
Define lung absces
necrosis of the lung tissue and formation of cavities containing necrotic debris or fluid caused by microbial infection
30
What organisms are more likely to cause a lung abscess
Staph. Aureus, pseudomonas and anaerobes
31
What are the symptoms of a lung abscess
usually non specific i.e. weight loss, high swimming fever, lethargic
32
How is a lung abscess investigated
Investigate with CT thorax and sputum culture
33
What is the treatment of lung abscess
prolonged antibiotics
34
Where is drainage usually taken from,
bronchial tree | occasionally percutaneous drainage necessary
35
What is the pathology of bronchiectasis
damaged dilated airways, due to thickened airway wall and mucus production
36
What is the aetiology of bronchiectasis
Idiopathic Immotile Cilia Syndrome Cystic fibrosis Childhood infections such as measles Hypogammaglobulinaemia - reduction in all types of gamma globulins, including antibodies that help fight infection Allergic Bronchopulmonary Aspergillosis (ABPA) - exaggerated response of the immune systemto the fungus Aspergillus
37
What is the symptoms of bronchiectasis
``` Chronic cough Daily sputum production (often copious) Sometimes, Wheeze Dyspnoea Tiredness Flitting chest pains Haemoptysis ```
38
What is the signs of bronchiectasis
Usually no signs Finger clubbing Course inspiratory crepitations - crackely noise (only heard on auscultation)
39
What investigations take place for bronchiectasis
``` High resolution CT Thorax Sputum culture Serum immunoglobulins Total IgE and Aspergillus precipitins CF genotyping ``` (investigations look for underlying cause)
40
What is the potentially microbiology of bronchiectasis
haemophilus influenzae, staph. aureus pseudomonas aeruginosa
41
What is the treatment for bronchiectasis
Chest physiotherapy Prompt treatment of infections with appropriate antibiotics inhaled therapy including beta2 agonist and inhaled corticosteroid.
42
When would chest physiotherapy be useful
when you have a lot of mucus
43
When would inhaled therapy be needed in the treatment of bronchiectasis
when wheezing becomes present
44
What is the pathology of acute bronchitis
inflammation of trachea and main airways
45
What is the usual cause of acute bronchitis
viral infection