Embryology (fertilisation, week 1 -2) Flashcards

(39 cards)

1
Q

How many sperm are allowed to penetrate the ovum

A

one

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2
Q

What is the products of oogensesis meiosis

A

1 ovum and 3 polar podies (X)

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3
Q

What is the product of spermogeneis meiosis

A

4 sperm bodies ( X/Y)

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4
Q

What is the first cell of the body

A

zygote

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5
Q

What fuses between the egg and the sperm

A

The pronucleases

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6
Q

What enters the ovum when the sperms pronucleus fuses

A

the sperms genetic material, everything else is left behind

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7
Q

Is mitochondiral cell organelles inherited by the paternal or maternal

A

Maternal

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8
Q

what is an example of a maternal mitochondrial inherited condition

A

Lebers hereditary optic neuropathy - blindness

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9
Q

What are the two processes that occur in week 1

A

The zygote divides to from a blastocyte

The zygote moves through the uterine tubes to the uterine cavity

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10
Q

The zygote divides by mitotsis forming a ball of cells called what?

A

morula

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11
Q

The central core of the mass of cells becomes harder forming a cavity through, what is this cavity called

A

blastolytic cavity

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12
Q

What is the cells that from the outer layer of the morula called

A

trophoblast

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13
Q

Where is the inner cell mass found in the morula

A

The cells that are accumulating at one end of the cell

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14
Q

The ovary releases the ovum and fertilisation occurs in the uterine tubes, what feature of the uterine tubes than allows the transport of the zygote to the uterine cavity

A

They have cillated epithelium to push zygote through uterine tube and into uterine cavity

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15
Q

When and where should the blastocyte be formed by

A

around 5-6 days when it reaches the uterine cavity

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16
Q

How long is the first division of the zygote to from the balstocyte

17
Q

What happens to the division time as it continues moving through the uterine tubes

A

Successful division take less time

18
Q

What should the blastocyte be ready to do when it reaches the uterine cavity

A

ready for implantation

19
Q

What hormones prepare the body form implantation

A

Progesterone and oestrogen produced by the ovary

20
Q

Due to what circumstance can ectopic pregnancy occur

A

cilia function is abnormal, so zygote implants in the uterine tubes rather than the uterine cavity, leading to a failure in the pregnancy as the uterine tube cant support it

21
Q

What is the differences between monozygotic and dizygotic twins

A
mono = 1 zygote, share placenta, genetically identical 
Di = 2 zygotes, different placentas, not genetically identical
22
Q

Where does implantation occur in the uterine cavity

A

in the endometrium layer

23
Q

By what day does the blastocyte burrow into the endomtetium

24
Q

The trophoblast divides to from 2 layers called what

25
What does the chorion chronic villi allow the trophoblast to do
Helps the implantation into the endometrium
26
What does the chronic vili of the trophoblast then go on to become for the embryo
the placenta
27
What is the part of the endometrium called which hold the burrowed blastocyte
Decidua
28
When the blastocyes implants in the endometrium these is an increase in blood vessels surrounding the chorion what are these blood vessels called
decidua basalis
29
What hormone does the chorion secrete and what is its function
secretes hormone human chorionic gonadotrophin HCG prevents endometrium sheding by infoming ovary to keep producing oestrogen and progesterone
30
What hormone is used to detect pregnancy
HCG
31
HCG levels increase until what week
12 weeks gestation
32
Are the chorion villi in contact with the maternal blood?
No, passage of nutrients occurs by diffusion
33
What is the main functions of the placenta
Foetal nourishment inspirit of waste and gas immune protection
34
How long does it take the placenta to mature
18 - 20 weeks
35
Where is the two surfaces of the placenta facing and what are they like?
maternal - desidua basalis (rough) | foetus - amniotic membrane attaching to the end of umbilicus chord (smooth)
36
What does the inner cell mass go on to from
Bilaminar disc
37
What two layers are divided by the bilaminar disc
the epiblast and the hypoblast
38
What cavity sits above the epiblast
the amniotic cavity (where the embryo develops)
39
What cavity sits below the hypoblast
Yolk sac