Lung Cancer Flashcards Preview

N420 Flashcards > Lung Cancer > Flashcards

Flashcards in Lung Cancer Deck (18):
1

What is nadir?

The lowest point reached in peripheral blood cell count after chemotherapy administration

2

__________ __________ is a consequence of the presence of cancer in the body. The effects are mediated by _______ factors excreted by tumor cells or by an immune response against the tumor.

Paraneoplastic syndrome

humoral (hormones, cytokines)

3

Name the types of primary lung cancer

NSCLC
Adenocarcinoma
Squamous cell carcinoma
Large cell carcinoma
SCLC
Small cell carcinoma

4

___________ is the most common type of lung cancer and has no ________ ________ until widespread metastasis is present.

Adenocarcinoma

clinical manifestations

5

_______ _______ _______ is the second most common lung cancer. It is a slow growing cancer that starts in the ________ ________ producing ________ characteristics.

Squamous cell carcinoma

Bronchial tubes

Obstructive

6

The least common form of NSCLC is ______ ______ ______ . This cancer commonly causes ______ and is highly metastatic via ______ and ______.

Large cell carcinoma

Cavitation

Lymphatics, Blood

7

Small cell carcinoma accounts for ____% of lung cancers and is the ______ ______ form of lung cancer. It tends to spread early via lymphatics and bloodstream.

20%

Most malignant

8

What does TNM stand for and what is is assessing?

T - TUMOR size, location and degree of invasion
N - Lymph NODE involvement
M - Presence or absence of distant METASTASES

Assesses the STAGE of the NSCLC

9

Surgical therapy is the treatment of choice for what NSCLC stages? Why?

Stages I and II, because it doesn't have mediastinal involvement (Pneumonectomy, Lobectomy, Segmental or wedge resection)

10

Radiation therapy

Can treat NSCLC or SCLC as curative or palliative or adjuvant

11

Sterotactic Radiotherapy

High doses delivered very accurately to tumor

12

Chemotherapy

Primary for SCLC. NSCLC chemo may be used in treatment of nonresectable tumors or as adjuvant.

13

Biologic and Targeted Therapy

Targeted therapy uses drugs that block the growth of molecules involved in specific aspects of tumor growth

14

Prophylactic Cranial Radiation

Most chemo does not penetrate the BBB therefore prophylactic radiation decreases the incidence of cerebral metastases

15

Bronchoscopic Laser Therapy

Used to remove obstructing bronchial lesions

16

Photodynamic therapy

Porfimer (Photofrin) is injected IV, concentrates in tumor, exposed to laser, produces toxic oxygen, destroys tumor cells, necrotic tissue removed

17

Airway stenting

Stents that relieve dyspnea, cough, respiratory insufficiency

18

Cryotherapy

Broncoscopic cryotherapy is used to ablate bronchogenic carcinoma