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Flashcards in Lung Cancer Deck (13):
1

what are types of non-small cell lung cancer (majority)

squamous cell carcinoma
adenocarcinoma
large cell carcinoma

2

what is characteristics of squamous cell carcinoma

hypertrophic pulmonary osteoarthropathy
most commonly cavitates

3

what is characteristics of adenocarcinomas

most common type
usually peripheral in bronchi

4

what is the characteristics of large cell carcinoma

typically peripheral, poorly differentiated tumours with poor prognosis, may secrete beta HCG

5

what is characteristics of small cell lung cancer

arises from endocrine cells
hormones secreted: ADH and ACTH
spreads early and almost always inoperable

6

what kind of state does malignant cancer (especially adenocarcinoma) cause

hypercoaguable state

7

what is symptoms

cough that lasts >2-3 weeks
long standing cough that gets worse
haemoptysis
unexplained dyspnoea
malaise
weight loss
persistent chest pain/shoulder pain

8

what are less common symptoms

clubbing, hoarse voice, difficulty or pain swallowing, increased risk of infection

9

what causes it

smoking
passive smoking
occupational exposure

10

how is it diagnosed

CXR
CT for small tumours and mediastinum (then biopsy)
FBC for anaemia
Urinanalysis

11

how to treat non small cell lung cancer

surgery
chemotherapy
radiotherapy
targeted agents

12

how to treat small cell lung cancer

chemotherapy, palliative care

13

what is common sites of metastases

kidney
prostate
breast
bone
GI tract
cervix or ovary