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Flashcards in male Path II Deck (42):
1

common spot for condyloma accuminata in men

coronal sulcus and inner surface prepuce

2

what is a sign of bowden disase

red or grey plaque on shaft
carcinoma in situ

3

what is erythroplasia of querat

shiny soft red plaque on glans and foreskin

4

all carcinomas in situ of penis have what in common

clinical variants of HPV 16

5

what are bowenoid papulosis

red tan papules in young adults. DOES NOT progress to invasive SCC

6

HPV E6 and e7

E6 inactivates p53
E7 inactivates pRB

7

koilocyte

high risk HPV

8

CIS of penis

bowens disease
erythroplasia of querat

9

risk factors SCC penis

lack of circumscision
assoc HPV 16 18
occurs between 40&70
association with smoking

10

prognosis SCC penis depends on

spread to regional lymph nodes

11

how do invasive SCC penis present

painless slow growing tumors

12

tumor Bx from penis show islands of keratin and "pearls"

invasive SCC

13

what are pearly penile papules

not HPV or genital wart
white papules in rows
disapears after years

14

dusky blue appearance over testicle in young boy complaining of pain

torsion of appendix testis

15

what is tunica albuginea

covers testis

16

where do hydroceles form

in scrotal cavity

17

what is it called if infection in scrotal cavity

pyocele

18

cryptorchidism

failure of testicle to descend into scrotum

19

phases of testicular descent

transabdominal (sertoli cells make AMH andwolffiant duct develops when T present)
inguinal-scrotal phase: craniosuspensory ligament dissolves and gubernaculum guides testis to scotum

20

what hormones are needed for testicular descent

1: AMH and T
2: androgens

21

cryptorchidism is assoc with

klinefelter, premature birth and +FMH

22

cryptorchidism patients are at higher risk for

testicular CA, trauma, torsion and infertility

23

Tx cryptorchidsm

surgical correction
orchiopexy

24

where are sertoli and leydig cells found

sertoli in the germ cell area
leydig in stroma

25

majority testicles that do not descend are located where

high scrotum>inguinal canal>abdomen

26

conditions assoc with b/l atrophy of testicles

chronic alcoholism, hypopituitarism, atherosclerosis, chemo, radiation, severe prolonged illness

27

on microscopy of testicle see leydig cell hyperplasia, peritubular fibrosis and only sertoli cells in the tubles

cryptorchid

28

what is eagle barrett syndrome

prune belly syndrome
have b/l cryptorchidism
absence abdominal muscles

29

in infant see severely swollen scrotum

torsion

30

which direction does testicular torsion usually occur

medially

31

how long do you have to recognize testicular torsion

12 hours

32

bell claper deformity

when testicle is in horizontal position

33

Dx torsion

doppler

34

what bacteria cause epididymitis in young men

gonorrhea, chlamydia

35

what bacteria cause epididymitis in old men

E coli from UTI

36

what infections affect testicle before epididymis

syphilis
mumps
gram - bacteria

37

best way to Dx infeciton of testicle or epididymis

culture UA

38

what can cause granulomatous orchitis

post vasectomy because seminal fluid gets around an into cavity

39

many PMNs in epididymal ducts

infection

40

what are the germ cell tumors

seminomatous
non seminomatous

41

what are the sex cord stromal tumors

leydig cell tumor and sertoli cell tumor

42

what lymphoma occurs in testicles

non hodgkin diffuse B cell lymphoma