Male Reproductive Physiology Flashcards

(32 cards)

1
Q

sexual excitement causes CNS activation of ___ neurons innervating internal pudendal arteries, causing release of nitric oxide (NO)

A

parasympathetic

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2
Q

During ejaculation, spinal reflex is initiated over sympathetic nerves serving genital organs, resulting in: (1)

A

ductus deferens, prostate, and seminal glands contract and empty contents into prostatic urethra; bladder internal sphincter muscle constricts, preventing expulsion of urine or reflux of semen into bladder

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3
Q

During ejaculation, spinal reflex is initiated over sympathetic nerves serving genital organs, resulting in: (2)

A

Semen in urethra triggers spinal reflex through
somatic neurons; bulbospongiosus muscles undergo rapid series of
contractions that cause expulsion of semen

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4
Q

latent (refractory) period

A

time during which man is unable to achieve another orgasm

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5
Q

erectile dysfunction

A

parasympathetic nerves of penis release too little NO, leading to inability to attain erection

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6
Q

spermatogenesis

A

process of forming male gametes; occurs in seminiferous tubules

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7
Q

Seminiferous tubules

A

consist of a thick stratified epithelium surrounding a central fluid-filled lumen containing four important types of cells

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8
Q

Seminiferous tubules contain four important types of cells:

A

sustenocytes, spermatogenic cells, myoid cells, interstitial endocrine cells

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9
Q

sustenocytes

A

large columnar cells act as supporting cells and play role in sperm formation

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10
Q

spermatogenic cells

A

cells that are surrounded by sustentocytes and give rise to sperm

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11
Q

myoid cells

A

smooth muscle-like cells surrounding seminiferous tubule that contract to squeeze sperm and testicular fluid through tubules

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12
Q

interstitial endocrine cells (Leydig cells)

A

produce androgens and some estrogen

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13
Q

three steps of spermatogenesis

A

mitosis of spermatogonia, meiosis, spermiogenesis

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14
Q

mitosis of spermatogonia (stem cell)

A

forms two spermatocytes

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15
Q

meiosis

A

spermatocytes form secondary spermatocytes, which form spermatids

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16
Q

spermiogenesis

A

spermatids become sperm

17
Q

spermatogonia

A

stem cells that are in direct contact with epithelial basal lamina that divide more or less continuously by mitosis

18
Q

After puberty, each division of stem cells produces:

A

Type A daughter cells (remain at basal lamina to maintain pool of dividing germ cells); Type B daughter cells (move toward lumen and develop into primary spermatocytes)

19
Q

meiosis

A

spermatocytes to spermatids

20
Q

spermiogenesis

A

spermatids to sperm

21
Q

contains hydrolytic enzymes that enable sperm to penetrate egg

A

acrosome (found in head of sperm)

22
Q

sperm midpiece

A

metabolic region containing mitochondria that produce ATP to move tail

23
Q

role of sustenocytes

A

large supporting cells extend from basal lamina to tubule lumen and surround developing spermatogonium

24
Q

sustentocytes contain tight junctions that divide tubule into two compartments

A

basal and adluminal

25
basal compartment
basal lamina to tight junctions; spermatogonia and primary spermatocytes located here
26
adluminal compartment
internal to tight junction; area where meiotically active cells and tubule lumen are located
27
tight junctions form the blood testis barrier
prevents sperm antigens from escaping into blood and causing activation of immune system
28
testicular fluid
rich in androgens and metabolic acid; secreted by sustenocytes
29
androgen-binding protein (ABP)
keeps testosterone levels high to stimulate spermatogenesis
30
referred to as the hypothalamic-pituitary-gonadal (HPG) axis
sequence of hormonal events involving hypothalamus, anterior pituitary gland, and testes that regulates the production of gametes and sex hormones
31
testosterone is converted to what in the prostate
digydrotestosterone (DHT)
32
testosterone is converted to what in some brain neurons
estradiol