Male Reproductive System Flashcards

(72 cards)

1
Q

Wollfian duct

A

Will form the vas deferens in males

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2
Q

Mullerian duct

A

Will form the oviduct/uterus in females

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3
Q

Male reproductive system consists of ______

A

testes, genital ducts, accessory glands, and penis

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4
Q

Testes

A

Have different cell types that (1) produce sperm and (2) secrete hormones
such as testosterone, which drives male reproductive physiology.

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5
Q

Cryptorchidism

A

The failure of one or both
testes to descend from the abdomen

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6
Q

Tunica albuginea

A

A dense connective tissue capsule that surrounds each testis

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7
Q

Testicular lobules

A

The testis is subdivided into about 250 compartments or testicular lobules. Each contains:

1-4 highly convoluted seminiferous tubules in which sperm production occurs.

Connective tissue, in the space between the tubules, with endocrine interstitial
cells (Leydig cells) secreting testosterone.

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8
Q

Seminiferous tubules

A

Produce sperm by spermatogenesis and spermiogenesis.

Each tubule is a loop linked by a short segment, the straight tubule, to the
rete testis, a maze of epithelium-lined channels.

Each seminiferous tubule is lined with a stratified epithelium called germinal or spermatogenic epithelium

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9
Q

“Germ cells” or spermatogenic cells

A

Develop into spermatozoa.

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10
Q

Sertoli cells

A

Form the epithelial walls; these nourish developing sperm cells.

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11
Q

Myoid cells

A

Contract the seminiferous tubules.

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12
Q

Spermatogenesis

A

Germ cells undergo a series of changes,
including reduction of chromosomes from 46 (diploid) to 23 (haploid), up to the spermatid stage.

Involves mitosis and meiosis.

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13
Q

Spermiogenesis

A

Spermatids transform to spermatozoa.

Follows spermatogenesis; it is the final differentiation
process.

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14
Q

Interstitial cells (Leydig cells)

A

Interstitial tissue between the tubules is sparse connective tissue containing interstitial cells (Leydig cells), which
produce testosterone.

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15
Q

Sertoli cells functions

A

Support, protection, and nutrition of the developing spermatogenic cells

Exocrine and endocrine secretion

Phagocytosis

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16
Q

Blood-testis barrier

A

Tight occluding junctions between the basolateral membranes of Sertoli cells form a blood-testis barrier. This prevents autoimmune
attacks against the unique spermatogenic cells, which appear after the immune system is mature and central self-tolerance is established.

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17
Q

Spermatogenesis &
Spermiogenesis Process

A

Type A spermatogonia

Type B spermatogonia

1° spermatocytes

2° spermatocytes

Spermatids

Spermatozoa

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18
Q

Testicular cancer

A

Most (95%) testicular cancer involves germ cell tumors, which only appear after puberty and are much more likely to develop in men
with untreated cryptorchidism.

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19
Q

Straight tubules

A

Function: Convey sperm into the rete testis

The seminiferous tubules drain into short, much narrower straight tubules, which connect to the rete testis

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20
Q

Rete testis

A

Function: Channels with sperm from all seminiferous tubules

A network of channels embedded along with blood vessels in the connective tissue of the mediastinum testis.

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21
Q

Efferent ductule

A

Function: Absorb most fluid form seminiferous tubules; convey sperm into the epididymis

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22
Q

Epididymal duct (Epididymis)

A

Function: Site for sperm maturation and short-term storage; expels sperm at ejaculation

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23
Q

Ductus (vas) deferens

A

Function: Carries sperm by rapid peristalsis from the epididymis to the ejaculatory ducts

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24
Q

Ejaculatory ducts

A

Function: Mix sperm and seminal fluid; deliver semen to urethra, where prostatic secretion is added

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25
Vasectomy
A very small incision is made through the scrotal skin near the two ducts and each vas deferens is exposed, cut, and the ends are cauterized and tied.
26
Semen
The mixture of spermatozoa and the secretions of seminal vesicles, prostate, and bulbourethral glands
27
Seminal Vesicles
Exocrine glands in which production of their yellowish secretion depends on testosterone. Seminal vesicle fluid typically makes up about 70% of the ejaculate. Its components include: Fructose, a major energy source for sperm Prostaglandins, which stimulate activity in the female reproductive tract Fibrinogen, which allows semen to coagulate after ejaculation.
28
Prostate Gland
A collection of 30-50 tubuloacinar glands embedded smooth muscle which contracts at ejaculation. A contributor to the volume of seme
29
Common prostate gland problems
Chronic prostatitis, usually involving bacteria. Nodular hyperplasia or benign prostatic hypertrophy, occurring mainly in the mucosal glands where it often leads to compression of the urethra and problems with urination. Prostate cancer (an adenocarcinoma), the most common cancer in nonsmoking men, occurring mainly in glands.
30
Bulbourethral Glands (Cowper glands)
Each gland has tubuloacinar secretory units surrounded by smooth muscle cells and lined by a mucus-secreting epithelium. During erection, release a clear mucus-like secretion that coats and lubricates the urethra for the imminent passage of semen.
31
Three erectile bodies
corpus spongiosum and two corpora cavernosa
32
Penile erection
Parasympathetic stimulation: relaxes the smooth muscle and dilates the tiny arteries, this enlarges the corpora cavernosa and causes them to compress the dorsal veins against the tunica albuginea, which blocks the venous outflow and produces tumescence (swelling) and rigidity in the erectile tissue. Sympathetic stimulation: Beginning at ejaculation, constricts the tiny arteries and trabecular muscle, decreasing blood flow into the spaces, lowering the pressure there, and allowing the veins to drain most blood from the erectile tissue.
33
Erectile dysfunction
At the beginning of an erection, acetylcholine from parasympathetic nerves causes the helicine arteries (tiny arteries) and erectile tissue to release a signaling molecule (cyclic GMP) that causes vasodilation. This molecule is degraded eventually by enzyme, relaxing the vasodilation. The drug sildenafil (Viagra) may alleviate the problem by inhibiting the enzyme that degrades cyclic GMP in the smooth muscle cells of the erectile tissue. This promotes relaxation of these cells to maintain an erection.
34
What is the main effect of benign prostatic hypertrophy?
Difficulty with urination.
35
What is the important function of the blood-testis barrier?
It prevents autoimmune attacks against the spermatogenic cells. These attacks occur because the innate immune system is established before spermatozoa begin to develop.
36
Which mass of erectile tissue surrounds the penile urethra?
Corpus spongiosum
37
The pathway of a spermatozoon from the seminiferous tubules to the urethra is:
Straight tubule, rete testis, efferent ductules, epididymis, vas deferens
38
The dense connective tissue capsule that surrounds each testis is called the
Tunica albuginea
39
Why is a male child with undescended testes likely to be come infertile?
The temperature within the body is too warm for sperm to develop properly.
40
# Reversed prompt Will form the vas deferens in males
Wollfian duct
41
# Reversed prompt Will form the oviduct/uterus in females
Mullerian duct
42
# Reversed prompt testes, genital ducts, accessory glands, and penis
Male reproductive system consists of \_\_\_\_\_\_
43
# Reversed prompt Have different cell types that (1) produce sperm and (2) secrete hormones such as testosterone, which drives male reproductive physiology.
Testes
44
# Reversed prompt The failure of one or both testes to descend from the abdomen
Cryptorchidism
45
# Reversed prompt A dense connective tissue capsule that surrounds each testis
Tunica albuginea
46
# Reversed prompt The testis is subdivided into about 250 compartments or testicular lobules. Each contains: 1-4 highly convoluted seminiferous tubules in which sperm production occurs. Connective tissue, in the space between the tubules, with endocrine interstitial cells (Leydig cells) secreting testosterone.
Testicular lobules
47
# Reversed prompt Produce sperm by spermatogenesis and spermiogenesis. Each tubule is a loop linked by a short segment, the straight tubule, to the rete testis, a maze of epithelium-lined channels. Each seminiferous tubule is lined with a stratified epithelium called germinal or spermatogenic epithelium
Seminiferous tubules
48
# Reversed prompt Develop into spermatozoa.
"Germ cells" or spermatogenic cells
49
# Reversed prompt Form the epithelial walls; these nourish developing sperm cells.
Sertoli cells
50
# Reversed prompt Contract the seminiferous tubules.
Myoid cells
51
# Reversed prompt Germ cells undergo a series of changes, including reduction of chromosomes from 46 (diploid) to 23 (haploid), up to the spermatid stage. Involves mitosis and meiosis.
Spermatogenesis
52
# Reversed prompt Spermatids transform to spermatozoa. Follows spermatogenesis; it is the final differentiation process.
Spermiogenesis
53
# Reversed prompt Interstitial tissue between the tubules is sparse connective tissue containing interstitial cells (Leydig cells), which produce testosterone.
Interstitial cells (Leydig cells)
54
# Reversed prompt Support, protection, and nutrition of the developing spermatogenic cells Exocrine and endocrine secretion Phagocytosis
Sertoli cells functions
55
# Reversed prompt Tight occluding junctions between the basolateral membranes of Sertoli cells form a blood-testis barrier. This prevents autoimmune attacks against the unique spermatogenic cells, which appear after the immune system is mature and central self-tolerance is established.
Blood-testis barrier
56
# Reversed prompt Type A spermatogonia Type B spermatogonia 1° spermatocytes 2° spermatocytes Spermatids Spermatozoa
Spermatogenesis & Spermiogenesis Process
57
# Reversed prompt Most (95%) testicular cancer involves germ cell tumors, which only appear after puberty and are much more likely to develop in men with untreated cryptorchidism.
Testicular cancer
58
# Reversed prompt Function: Convey sperm into the rete testis The seminiferous tubules drain into short, much narrower straight tubules, which connect to the rete testis
Straight tubules
59
# Reversed prompt Function: Channels with sperm from all seminiferous tubules A network of channels embedded along with blood vessels in the connective tissue of the mediastinum testis.
Rete testis
60
# Reversed prompt Function: Absorb most fluid form seminiferous tubules; convey sperm into the epididymis
Efferent ductule
61
# Reversed prompt Function: Site for sperm maturation and short-term storage; expels sperm at ejaculation
Epididymal duct (Epididymis)
62
# Reversed prompt Function: Carries sperm by rapid peristalsis from the epididymis to the ejaculatory ducts
Ductus (vas) deferens
63
# Reversed prompt Function: Mix sperm and seminal fluid; deliver semen to urethra, where prostatic secretion is added
Ejaculatory ducts
64
# Reversed prompt A very small incision is made through the scrotal skin near the two ducts and each vas deferens is exposed, cut, and the ends are cauterized and tied.
Vasectomy
65
# Reversed prompt The mixture of spermatozoa and the secretions of seminal vesicles, prostate, and bulbourethral glands
Semen
66
# Reversed prompt Exocrine glands in which production of their yellowish secretion depends on testosterone. Seminal vesicle fluid typically makes up about 70% of the ejaculate. Its components include: Fructose, a major energy source for sperm Prostaglandins, which stimulate activity in the female reproductive tract Fibrinogen, which allows semen to coagulate after ejaculation.
Seminal Vesicles
67
# Reversed prompt A collection of 30-50 tubuloacinar glands embedded smooth muscle which contracts at ejaculation. A contributor to the volume of seme
Prostate Gland
68
# Reversed prompt Chronic prostatitis, usually involving bacteria. Nodular hyperplasia or benign prostatic hypertrophy, occurring mainly in the mucosal glands where it often leads to compression of the urethra and problems with urination. Prostate cancer (an adenocarcinoma), the most common cancer in nonsmoking men, occurring mainly in glands.
Common prostate gland problems
69
# Reversed prompt Each gland has tubuloacinar secretory units surrounded by smooth muscle cells and lined by a mucus-secreting epithelium. During erection, release a clear mucus-like secretion that coats and lubricates the urethra for the imminent passage of semen.
Bulbourethral Glands (Cowper glands)
70
# Reversed prompt corpus spongiosum and two corpora cavernosa
Three erectile bodies
71
# Reversed prompt Parasympathetic stimulation: relaxes the smooth muscle and dilates the tiny arteries, this enlarges the corpora cavernosa and causes them to compress the dorsal veins against the tunica albuginea, which blocks the venous outflow and produces tumescence (swelling) and rigidity in the erectile tissue. Sympathetic stimulation: Beginning at ejaculation, constricts the tiny arteries and trabecular muscle, decreasing blood flow into the spaces, lowering the pressure there, and allowing the veins to drain most blood from the erectile tissue.
Penile erection
72
# Reversed prompt At the beginning of an erection, acetylcholine from parasympathetic nerves causes the helicine arteries (tiny arteries) and erectile tissue to release a signaling molecule (cyclic GMP) that causes vasodilation. This molecule is degraded eventually by enzyme, relaxing the vasodilation. The drug sildenafil (Viagra) may alleviate the problem by inhibiting the enzyme that degrades cyclic GMP in the smooth muscle cells of the erectile tissue. This promotes relaxation of these cells to maintain an erection.
Erectile dysfunction