Flashcards in Management of acute otitis media in children six months of age and older Deck (23):
Why are children predisposed to AOM?
1. More frequent viral infections
2. Shorter eustachian tubes
3. More horizontal eustachian tubes
What are risk factors for AOM?
1. Young age
2. Frequent contact with other children
3. Orofacial abnormalitis i.e. cleft palate
4. Household crowding
5. Exposure to cigarette smoke
6. Pacifier use
7. Shorter duration of breastfeeding
8. Prolonged bottle-feeding while lying down
9. Family history of otitis media
10. Children of First Nations or Inuit ethnicity
11. Lower levels of secretory IgA
12. Persistent biofilm in middle ear
What are the most common bacteria causing AOM?
1. S. pneumoniae
2. H. influenzae
3. M. catarrhalis
4. GAS (less commonly)
What symptoms are associated with AOM?
1. Poor sleep
2. Decreased activity
What are methods to diagnose of middle ear effusion?
1. Decreased TM mobility when both positive and negative pressure applied using a pneumatic otoscope
2. Automated tympanometry is unrealiable in infants <7mo and sensitivty and specificity depends on proper use and information
3. Otoscopy showing
a) loss of bony landmarks
b) presence of air-fluid level
c) Bulging TM
d) Red or yellow TM
What are the diagnostic criteria for AOM?
1. Acute onset of symptoms (otalgia, or non-specific in non-verbal children)
2. Signs of middle ear effusion
3. WITH signs of inflammation of the middle ear (moderate or marked bulging of TM with marked erythema, hemorrhage, or yellow TM)
Which bacteria is associated with spontaneous TM perforation?
What is the DDx of ear drainage?
1. Perforation from AOM
2. Otitis externa
3. Chronic ear drainage from previous perforation
4. Drainage from T-tube
What are common complications of bacterial AOM?
1. Acute mastoiditis (pain and swelling over the mastoid)
2. Acute facial (CN VII) nerve palsy from temporal bone inflammation
3. Gradenigo's syndrome: 6th CN palsy (failure of ipsilatral eye abduction) due to petrous bone inflammation or infection
4. Labryinthitis due to spread to cochlear space
5. Venous sinus thrombosis of transverse, lateral or sigmoid venous sinuses
What is the management of patients with spread beyond the middle ear?
1. Systematic antimicrobial therapy
2. Consider surgical intervention
3. Consider imaging to deliniate the extent of the infection
What are the treatment recommendations for patients presenting with a perforated TM with symptoms of AOM?
1. Systemic antimicrobials x 10d
2. Examination for associated complications
What does mildly ill mean in the context of AOM?
3. No rigors
4. Responding to anti-pyretics
5. Mild otalgia
6. Able to sleep
7. <39 degrees C in absence of antipyretics
8. <48h of illness
What does moderately or severely ill mean in the context of AOM?
2. Difficulty sleeping
3. Poor response to antipyretics
4. Severe otalgia
5. >39 degrees C in absence of antipyretics
6. >48h of symptoms
What are the treatment recommendations for patients with MEE present AND bulging TM who are mildly ill?
1. Discuss with caregivers
2. Observe for 24-48h and ensure f/u
3. Recommend analgesia
4. If not improved or worsening clinically, treat with antimicrobials (6m-2yo x 10d, >2y x5d)
What are the treatment recommendations for patients with MEE present AND bulging TM who are moderately or severely ill?
Treat with antimicrobials:
1. 6m-2yo x 10d
2. >2yo x 5d
What are the treatment recommendations for patients without MEE OR with MEE but non-bulging or mildly erythematous TM?
1. Consider viral etiology (i.e. RSV, influenza) or other infection
2. r/a in 24-48h if not clinically improving or earlier if worsening clinically to verify presence of effusion and signs of middle ear inflammation such as bulging TM
What are the recommendations if unable to determine if TM bulging?
1. only mildly ill
2. does not appear to have severe otalgia
3. feeding reasonably well
4. T <39 degrees C for <24h
5. Reliable caregivers
Observe w/ f/u in 24-48h
Which bacteria cause AOM more likely to resolve spontaneously?
1. M catarrhalis
2. H influenza
What is the first line treatment for AOM (no penicillin allergy)?
Amoxicillin 75-90mg/kg/day PO BID OR 45-60mg/kg/day PO TID
What is the first line treatment if penicillin allergic?
1. Cefuroxime 30mg/kg/day PO BID or TID
2. Ceftriaxone 50mg/kg IM/IV daily x 3d
What is the therapy if initial therapy fails (no symptomatic improvement after 2-3 days)?
<35kg: Amoxicillin-clavulanate 45-60mg/kg/day PO TID x 10d (400mg/5mL suspension of 7:1 formulation)
>35kg: 500mg PO TID x 10d
What is the therapy if patient unable to tolerate oral antimicrobials or if amoxi-clav fails?
Ceftriaxone 50mg/kg/day IM/IV daily x 3d