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Immunology Exam Two > Memory > Flashcards

Flashcards in Memory Deck (42)
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1

What is the most important biological consequence of adaptive immunity?

Immunological memory

2

What are the longest lived antibodies?

IgG

3

How long do the longest lived antibodies live?

Month or two

4

What are the three kinds of B cells?

Short-lived plasma cell, long-lived plasma cell (memory cell), central memory B cell

5

What is required in order for the generation of both kinds of memory B cells to occur?

T cell help

6

What are the two kinds of memory B cells?

Long-lived plasma cell, central memory B cell

7

Where are short-lived plasma cells formed?

Lymphoid follicles of secondary lymphoid organs

8

What is the function of short-lived plasma cells?

Produce incredible amounts of antibodies

9

What is the life span of short-lived plasma cells?

Few days

10

To where do short-lived plasma cells travel?

Bone marrow and spleen

11

Where are long-lived plasma cells produced?

Lymphoid follicles of secondary lymphoid organs

12

To where do long-lived plasma cells travel to and take up residence?

Bone marrow

13

What is the function of long-lived plasma cells?

Continuously produce modest amounts of antibodies
Provide life-long antibody protection

14

Which B cell is used for measuring titers?

Long-lived plasma cells

15

Why do long-lived plasma cells live longer?

They aren't worked as hard

16

Which make more antibodies: short or long-lived plasma cells?

Short-lived

17

What kind of B cells function as memory stem cells?

Central memory B cells

18

Where do central memory B cells reside?

Mainly in secondary lymphoid organs

19

What kinds of cells replace long-lived plasma cells when they die from old age?

Central memory B cells

20

If an invader is encountered again, what do central memory B cells do?

Quickly proliferate and make more short-lived plasma B cells

21

Do central memory B cells usually quickly proliferate?

No; usually slowly unless in the presence of previous invader

22

Which kind of B cell provides life-long antibody protection?

Long-lived plasma cell

23

What kind of T cells travel to a battle site and fight?

Effector T cells

24

What kind of memory T cells travel to a battle site and remain there?

Memory effector T cells

25

What kind of activated T cells stay in the secondary lymphoid organs and bone marrow after activation?

Central memory T cells

26

What happens to central memory T cells during subsequent attacks?

Quickly activate and proliferate mostly into effector T cells, then go to battle site

27

Which are easier to activate: memory B and T cells or naive B and T cells?

Memory B and T cells

28

Why is somatic hypermutuation of memory B cells important?

Creates better antibody receptors fit to the invader for an "upgraded" fight

29

Why is class switching of memory B cells important?

Remains imprinted on the memory B cell to be better suited for the invader

30

What type of memory cells are fine tuned through somatic hypermutation?

B memory cells