Memory Flashcards
What is the most important biological consequence of adaptive immunity?
Immunological memory
What are the longest lived antibodies?
IgG
How long do the longest lived antibodies live?
Month or two
What are the three kinds of B cells?
Short-lived plasma cell, long-lived plasma cell (memory cell), central memory B cell
What is required in order for the generation of both kinds of memory B cells to occur?
T cell help
What are the two kinds of memory B cells?
Long-lived plasma cell, central memory B cell
Where are short-lived plasma cells formed?
Lymphoid follicles of secondary lymphoid organs
What is the function of short-lived plasma cells?
Produce incredible amounts of antibodies
What is the life span of short-lived plasma cells?
Few days
To where do short-lived plasma cells travel?
Bone marrow and spleen
Where are long-lived plasma cells produced?
Lymphoid follicles of secondary lymphoid organs
To where do long-lived plasma cells travel to and take up residence?
Bone marrow
What is the function of long-lived plasma cells?
Continuously produce modest amounts of antibodies
Provide life-long antibody protection
Which B cell is used for measuring titers?
Long-lived plasma cells
Why do long-lived plasma cells live longer?
They aren’t worked as hard
Which make more antibodies: short or long-lived plasma cells?
Short-lived
What kind of B cells function as memory stem cells?
Central memory B cells
Where do central memory B cells reside?
Mainly in secondary lymphoid organs
What kinds of cells replace long-lived plasma cells when they die from old age?
Central memory B cells
If an invader is encountered again, what do central memory B cells do?
Quickly proliferate and make more short-lived plasma B cells
Do central memory B cells usually quickly proliferate?
No; usually slowly unless in the presence of previous invader
Which kind of B cell provides life-long antibody protection?
Long-lived plasma cell
What kind of T cells travel to a battle site and fight?
Effector T cells
What kind of memory T cells travel to a battle site and remain there?
Memory effector T cells
