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Flashcards in Micro Deck (74)
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1

What is diptheria casued by? Where are the primary manifestations?

Cor-y-ne-bacterium Diphtheriae...NASO AND OROPHARYNX!!

2

What are the three sequential treatments for the treatment of acute diptheria?

1.Diptheria antitoxin (passive immunization) 2.Penicillin or erythromycin 3.DPT vaccine (active immunization)

3

What is the 3 stage life cycle of HEP B?

DS DNA --> +RNA template --> DS DNA progeny

4

What is the 3 stage replication cycle of HERPES?

DS DNA-->DS DNA template-->DS DNA progeny

5

Gram negative coccobacilli causing swelling of the right knee..what bacterium and what is its main virulence factor?

H. Influenzae and a CAPSULE

6

Haemophilus influenzae LOVES ______ and it requires both ___ factor and ___ factor to grow

BLOOD. X factor and V factor

7

What is the most common cause of ASEPTIC meningitis? what are the typical CSF protein and glucose levels?

Enteroviruses...modestly elevated protein, normal glucose

8

In bacterial meningitis, what are the two main bugs causing it in ADULTS? What are the CSF glucose and protein levels like?

Strep Pneumo and N. Meningitidis...elevated protein, low glucose

9

If I use cardiolipin, lecithin and cholesterol and observe extensive flocculation, what bug am I testing for?

Treponema pallidum (syphilis)

10

What virus is notorious for outbreaks in crowded quarters? What is the main clinical presentation? What type of DNA/RNA does it have?

ADENOVIRUS..pharyngo-conjunctival fever...DS-DNA

11

COOL: What species of bug causes terminal hematuria, dysuria, and frequent urination, hydronephrosis, pyeloneprosis, and SSC of the bladder? Found in Africa and Mid-East? UH. WHAT ORGANISM INFECTS HUMANS?

SCH-IS-TO-SO-MIA-SIS Hae-mat-o-bi-um..Freakin freshwater snails bro

12

What about the Hep C genome yields genetic variation in its envelope antigen?

Hep C is RNA and has no proofreading mechanism

13

What component of the human cell is the target for C. Diff's toxins A and B?

the cytoskeleton (toxins distrupt actin cytoskeleton structure)

14

What is the main lab tool used to differentiate Strep and Staph?

STREP=catalase NEGATIVE...Staph = catalase POSITIVE

15

AWESOME, you got the association between S. Aureus and yellow-honey crust on a cutaneous wound...but now...what is this condition called?

IMPETIGO

16

What bug is most commonly associated with intraabdominal abscesses following abdominal trauma or surgery? (endometriosis and complications of gynecologic procedures)

Bacterioides Fragilis

17

What are the three most common associated diseases with GROUP B Strept?

1.Neonatal Sepsis 2.Chorioamnionitis 3.Endometriosis (ALL BIRTHING THINGS!)

18

What bug underlies skin diseases like ecthyma gangrinosum, HOT TUB folliculitis (lol), pyoderma, green nail syndrome, and botryomycosis?

Pseudonomas Aeruginosa (aeruginosa means copper-green rust) (look up in latin book at home lol)

19

COOL! A bug NOT trying to kill us! _______ is a normal component of skin flora and if found in wound culture is considered a contaminant

Staphylococcus Epidermidis

20

INTERESTING! Mechanism of Action for Antibiotic Resistance...In general most ABX freely cross bacterial membranes, so what is the most common method for resistance?

Bacterial ability to PUMP (through H+, ATP, or Na+ gradient channels)

21

DNA viruses have diploid or haploid DNA?

haploid

22

________ are very small bacteria that have single, circular DNA genomes...INTERESTING, research has shown that these MAY have evolved from gram + bacteria!

MYCOPLASMAS

23

Since one mechanism of APOPTOSIS is the inability to perform new translation of proteins, the proteins that are required to be translated need an alternate method WHICH IS....???

INTERNAL RIBOSOME ENTRY

24

Which sequence (hint-someone's name) helps initiate translation in EUKARYOTES?

KOZAK consensus sequence

25

Which sequence (hint-scientist names) helps initiate translation in PROKARYOTES?

Shine-DalGARno sequence

26

Papallomaviruses: small or large?

small

27

Papallomaviruses: enveloped or nonenveloped?

nonenveloped

28

Papallomavirus: what type of genome?

CIRCULAR, DOUBLE-STRANDED DNA

29

Viral proteins inactivate ____ and ___ proteins, thus causing the cell to enter S-phase

p53 and Rb

30

OOOO INTERESTING!!! _____ viruses (((***EXCEPT FOR ______***))) replicate in the NUCLEUS

DNA....except for POXVIRUSES