Phys Flashcards Preview

(CBSE) All Subjects > Phys > Flashcards

Flashcards in Phys Deck (75)
Loading flashcards...
1

What is the nemonic for CARDIAC TISSUE CONDUCTION VELOCITY?

Park At VENTure AVenue (Purkinje->Atrial Muscle->Ventricular Muscle->AV node

2

WHEELHOUSE: which cytokine is produced EXLUSIVELY by lymphocytes??

IL-2

3

IL-1 is primarily produced by mononuclear ________

macrophages (so i shouldn't look for it in HGF's??lol)

4

TNF-a is a cytokine primarily produced by activated _______

macrophages

5

_______ is a cytokine chiefly generated by monocytes, macrophages, B cells, and NK cells and has numberous ANTIVIRAL functions

Interferon-alpha (IFN-a)

6

OOOO you should look for this primer with your HGF's!! ____ is a cytokine secreted by macrophages, T-cells, NK cells, mast cells, endothelial cells, and FIBROBLASTS and stimularws production of granulocytes and monocytes...

GM-CSF (granulocyte-macrophage colony-stimulating factor)

7

Desmosomes rely on ________ vs hemidesmosomes rely on _______ for connections

desmosomes = cadherins...hemidesmosomes = integrins

8

Bullous phemphigoid is associated with ________ whereas Pemphagus vulgaris is associated with ______

goid=hemidesmosomes...gus=desmosomes

9

Phospholipase C (PLC) activation is a step in the _______ second messenger system

inositol triphosphate (IP3)

10

What is the immediate step in tyrosine kinase signaling activity?

DIMERIZATION after the ligand binds to the receptor

11

Disorders of Sexual Development: X-linked mutation of androgen receptor, breast development, absent uterus/upper vagina/cryptorchid testes, absent pubic heair, karyotype 46, XY

COMPLETE ANDROGEN INSENSITIVITY SYNDROME (testosterone receptors thoughout the body are nonfxn)

12

Disorders of Sexual Development: Hypoplastic or absent mullarian ductal system, breast development, absent or rudementary uterus/upper vagina/normal overies, normal pubic hair, karyotype 46, XX

Mullarian Agenesis

13

Disorders of Sexual Development: Malformation of urogenital sinus and Mullarian ducts, breast development, normal uterus, abnormal vagina, normal overies, normal pubic hair, karyotype 46, XX

Transverse Vaginal Septum

14

Disorders of Sexual Development: Complete/partial absense of 1 X chromosome, variable breast dev, normal uterus/vagina/streak overies, normal pubic hair, karyotype 45,X

Turner Syndrome

15

Which type of pneumocyte makes up 97% of alveolar surfaces?

Type I pneumocyte

16

Which type of pneumocyte secretes pulmonary surfactant?

Type II pneumocyte

17

What is the difference between Adult Hemogobin and Fetal Hemoglobin

Adult = 2 alpha and 2 beta chains...Fetal = 2 alpha 2 gamma

18

Hemoglobin Barts is incompatable with life because the fetus is missing what components?

The fetus is missing BOTH alpha chain genes and therefore cannot release oxygen

19

Which cells are responsible for making ABP (androgen-binding protein)? What hormone stimulates them?

Sertoli Cells...FSH

20

What cells secrete testosterone?

Leydig cells

21

Glucagon binds to G protein-coupled receptors on hepatocytes, avictating ___, which in turn stimulates _______ to increase intracellular _______ levels

Gs...adenylate cyclase...cyclic AMP (cAMP)

22

cAMP activates _______ which leads to the activation of key enzymes in glycogenolysis, and gluconeogenesis

protein kinase A

23

Huh, interesting...what nerve would you electrocoagulate to stop excessive axillary sweating?

thoracic SYMPATHETIC trunk at the T2 segment

24

Michaelis-Menten kinetics: an INCREASE in the amount of ENZYME available in a system will cause an INCREASE in _____, but NO CHANGE in ___

increase in Vmax, no change in Km

25

Lineweaver-Burke: A reversible competitiive inhibitor- ____ of the enzyme INCREASES, while ____ remains UNCHANGED

Km...Vmax

26

Lineweaver-Burke: non competitive inhibitor- ____ DECREASES, ____ remains the same

Vmax...Km

27

Lineweaver-Burke: UNcompetitive inhibitor (can only bin to enzyme-substrate complex), ___ and ____ DECREASE, with NO CHANGE in the slope and therefore a Parallel line with a higher Y intercept

Km and Vmax

28

Which pathway does PROTHROMBIN TIME measure?

EXTRINSIC pathway (VII)

29

_____ kinases promote the synthesis and phosphorylation of transcription factors that control the entry of cells into the cell division cycle.

MAP kinase (mitogen-activated protein)

30

____ is a common SECOND MESSENGER in a G protein-coupled receptor signal transduction pathway. The FIRST effector molecule is PHOSPHOLIPASE C-gamma

DAG (diacylglycerol)