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Flashcards in Pharm Deck (96)
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1

What medication can shorten the course of influenza A and B if taken within 48 hrs? What is the MechOfAction?

OS-ELT-AM-IVIR (Tamiflu)..neuraminidase inhibition

2

What is the most common side effect of elderly patients and benzodiazapenes?

confusion! (insomnia is not an adverse effect)

3

What is an IRREVERSIBLE, long-acting, alpha-adrenergic BLOCKER that prevents peripheral vasoconstriction and is therefore used to resect a PHEOCHROMOCYTOMA which is spewing out EPI???

PHEN-OXY-BENZ-AMINE

4

Which CHEMO drug is notorious for causing TINNITUS and hearing loss??

Cis-Platin

5

What is a common antiemetic drug Rx'd to Pt's on chemo?

ON-DAN-Set-Ron

6

Name that Chemo Drug based on its side effects: vertigo and psychosis

glucocorticoids (prednisone)

7

Name that Chemo Drug based on its side effects: alopecia, GI irritation and myelosupression

E-TOP-O-SIDE

8

Name that Chemo Drug based on its side effects: Alopecia, MYOCARDIAL DAMAGE, and myelosuppression

DOX-O-RUBICIN

9

Name that Chemo drug based on its side effects: myelosuppression and FATTY change in the liver

METH-o-TREX-ate

10

HEY, one of my pt's is on this...What med can cause intersitial pneumontits (dyspnea, cough, dry inspiritory crackels)?

AMIDARONE (antiarythmic agent)

11

_______ and other anticoagulant agents can predispose patients to diffuse alveolar hemorrhage (DAH)

API-X-ABAN

12

What are the two main side effects of HydroxyChloroquine?

1.skin pigmentation changes and 2.retinopathy

13

LONG TERM prednisone use is associated with ________ syndrome

Cushing's

14

The two main adverse effects of SOTALOL include:

1. torsades de pointes 2.excessive beta blockade

15

What receptor in the stomach does MISO-PRO-STOL affect?

Prostaglandin E receptors

16

WHY do NSAIDS cause gastric ulcers???

NSAIDS block COX1. W/o COX 1 no prostaglandins are made. No prostaglandins = less MUCUS secretion in stomach

17

What is a good med to combat NSAID induced peptic ulcer?

Miso-Pro-Stol (no not miso soup, which is good for your stomach too :))

18

What are two examples of HISTAMINE blockers used to treat stomach acid?

Cim-et-IDINE and Ran-it-IDINE (get it!? the end in INE, like histamINE!!)

19

ASPIRIN-exacerbated airway disease: 10% of pt with asthma and is caused by DYSREGULATION of _________ metabolism due to __________ inhibition.

Arachidonic Acid metabolism...CycloOxygenase inhibition

20

IF you BLOCK COX 1,2 via Aspirin you can make more Leukotrienes via WHAT ENZYME???

5-LipOxyGenase

21

PLEASE NAME the progression of Membrane Phospholipids to Leukotrienes: Membrane Lipids--->________ enzyme--->_________ intermediate---->________enzyme---->Leukotrienes

Membrane PHOSPHOlipids--->PHOSPHOLIPASE A2--->Arachadonic Acid--->5-Lipoxygenase--->Leukotrienes

22

PLEASE NAME the progression from membrane phospholipids to PROSTAGLANDINS: Membrane phospholipids--->_________ enzyme----->______intermediate---->_______ enzyme---->Prostaglandins

Membrane Phospholipids--->phospholipase A--->arachadonic acid--->cyclooxegenase 1 and 2---> Prostaglandins

23

What is a good med for aspirin-exacerbated airway disease?

montelukast (singulair)

24

After administration of Nitroglycerin for Angina, what happens to HR and End-Diastolic Left Ventricular Volume?

HR = INCREASE (no direct effect, but REFLEX tachycardia)...End-diastolic left ventricular Volume = decrease

25

What is the category of drug for indomethacin and what is it used for?

an NSAID...Prostaglandin E antagonist... INTERESTING: can be used to close a patent ductus arteriosis

26

the AntiTB drug Isoniazid can induce a pyridoxine deficiency...so vitamin ___ supplementation is required with this drug!

B6

27

_________ disease is caused by a defect in the branched-chain alpha-keto acid dehydrogenase complex

MAPLE SYRUP URINE disease mmmmm

28

Severe flushing or diarrhea assoiciated with CARCINOID syndrome can be tx'd with _______, which is a _______ analog that functions by inhibiting the release of bioactive peptides by the carcinoid tumor

OCT-REO-TIDE...somatostatin

29

______ is a pretreatment useful in reducing cutaneous flushing in patients taking niacin

ASPIRIN

30

________ is a prodrug ANTIHISTAMINE associated with QT PROLONGATION in some patients!! (REMOVED FROM US MARKET)

TERF-EN-ADINE