Flashcards in Pharm Deck (96)
What medication can shorten the course of influenza A and B if taken within 48 hrs? What is the MechOfAction?
OS-ELT-AM-IVIR (Tamiflu)..neuraminidase inhibition
What is the most common side effect of elderly patients and benzodiazapenes?
confusion! (insomnia is not an adverse effect)
What is an IRREVERSIBLE, long-acting, alpha-adrenergic BLOCKER that prevents peripheral vasoconstriction and is therefore used to resect a PHEOCHROMOCYTOMA which is spewing out EPI???
Which CHEMO drug is notorious for causing TINNITUS and hearing loss??
What is a common antiemetic drug Rx'd to Pt's on chemo?
Name that Chemo Drug based on its side effects: vertigo and psychosis
Name that Chemo Drug based on its side effects: alopecia, GI irritation and myelosupression
Name that Chemo Drug based on its side effects: Alopecia, MYOCARDIAL DAMAGE, and myelosuppression
Name that Chemo drug based on its side effects: myelosuppression and FATTY change in the liver
HEY, one of my pt's is on this...What med can cause intersitial pneumontits (dyspnea, cough, dry inspiritory crackels)?
AMIDARONE (antiarythmic agent)
_______ and other anticoagulant agents can predispose patients to diffuse alveolar hemorrhage (DAH)
What are the two main side effects of HydroxyChloroquine?
1.skin pigmentation changes and 2.retinopathy
LONG TERM prednisone use is associated with ________ syndrome
The two main adverse effects of SOTALOL include:
1. torsades de pointes 2.excessive beta blockade
What receptor in the stomach does MISO-PRO-STOL affect?
Prostaglandin E receptors
WHY do NSAIDS cause gastric ulcers???
NSAIDS block COX1. W/o COX 1 no prostaglandins are made. No prostaglandins = less MUCUS secretion in stomach
What is a good med to combat NSAID induced peptic ulcer?
Miso-Pro-Stol (no not miso soup, which is good for your stomach too :))
What are two examples of HISTAMINE blockers used to treat stomach acid?
Cim-et-IDINE and Ran-it-IDINE (get it!? the end in INE, like histamINE!!)
ASPIRIN-exacerbated airway disease: 10% of pt with asthma and is caused by DYSREGULATION of _________ metabolism due to __________ inhibition.
Arachidonic Acid metabolism...CycloOxygenase inhibition
IF you BLOCK COX 1,2 via Aspirin you can make more Leukotrienes via WHAT ENZYME???
PLEASE NAME the progression of Membrane Phospholipids to Leukotrienes: Membrane Lipids--->________ enzyme--->_________ intermediate---->________enzyme---->Leukotrienes
Membrane PHOSPHOlipids--->PHOSPHOLIPASE A2--->Arachadonic Acid--->5-Lipoxygenase--->Leukotrienes
PLEASE NAME the progression from membrane phospholipids to PROSTAGLANDINS: Membrane phospholipids--->_________ enzyme----->______intermediate---->_______ enzyme---->Prostaglandins
Membrane Phospholipids--->phospholipase A--->arachadonic acid--->cyclooxegenase 1 and 2---> Prostaglandins
What is a good med for aspirin-exacerbated airway disease?
After administration of Nitroglycerin for Angina, what happens to HR and End-Diastolic Left Ventricular Volume?
HR = INCREASE (no direct effect, but REFLEX tachycardia)...End-diastolic left ventricular Volume = decrease
What is the category of drug for indomethacin and what is it used for?
an NSAID...Prostaglandin E antagonist... INTERESTING: can be used to close a patent ductus arteriosis
the AntiTB drug Isoniazid can induce a pyridoxine deficiency...so vitamin ___ supplementation is required with this drug!
_________ disease is caused by a defect in the branched-chain alpha-keto acid dehydrogenase complex
MAPLE SYRUP URINE disease mmmmm
Severe flushing or diarrhea assoiciated with CARCINOID syndrome can be tx'd with _______, which is a _______ analog that functions by inhibiting the release of bioactive peptides by the carcinoid tumor
______ is a pretreatment useful in reducing cutaneous flushing in patients taking niacin