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Flashcards in Path Deck (148)
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1

What is characterized by the development of hypoxemia and bilateral pulmonary infiltrates in the ABSENCE of heart failure??

ARDS-Acute Respiratory Distress Syndrome

2

What is a Kimmelsteil-Wilson lesion associated with? **Nodular** (mesangial expansion, glomerular basement membrane thickening, and glomerular sclerosis)

Diabetic Neuropathy

3

What is the bone tumor most often associated with Paget's Disease?

OSTEOSARCOMA

4

What are fragile mucosal folds that cause solid food dysphagia, usually in the mid to lower esophagus? What deficiency (Plummer-Vinson Syndrome) is it commonly seen?

Esophageal Web..iron

5

Histologically, what are these signs pointing to? acute inflammatory monoarthritis, neutrophilic effusion, and numerous needle-shaped crystals?

GOUT dawg!

6

What is the most common location for an endometrial cyst?

ovaries

7

Which vitamin supplementation is NOT advised during pregnancy?

Vitamin A..it can be teratogenic in excess!

8

MOST follicular __ ____ _______ are associated with a t(14;18) translocation that leads to BCL2 over expression (BCL2 overexp=evasion of apoptosis)

B cell lymphomas

9

What disease is characterized by AUER bodies and is a t(15;17) chromosomal translocation?

APL-Acute Promyelocytic Leukemia

10

Which disease is associated with a t(8;14) translocation and classically has round nuclei, basophillic cytoplasm, and prominiant lipid vacuoles?

Burkitt lymphoma

11

What is characteristic of a t(9;22) translocation and shows leukocytosis with many immature myeloid cells?

CHRONIC myeloGenous leukemia

12

What is the MOST COMMON translocation in childhood B-cell ACUTE LYMPHOCYTIC LEUKEMIA? (Peripheral blood smear=anemia, thrombocytopenia, and lymphoblasts)

t(12;21)

13

What form of leukemia am I? malignant cells with notches or clefts and a t(14;18) translocation?

Follicular lymphoma

14

Which viral infection is associated with ballooning multinucleated giant cells?

Herpes Simplex

15

Which carcinoma presents with cells at the periphery displaying parallel alignment (palisading)?

basal cell carcinoma

16

Which infection shows histologically with perinuclear HALOS?

Verruca Vulgaris

17

Get ready for a new one...What is associated with umbilicated, flesh-colored papules on the skin and mucous membranes? Uh..WHATS ITS CAUSAL AGENT???

Molluscum Contagiosum (wtf?)...poxvirus

18

What is the most important risk factor for postpartum endometriosis? What organ? What bugs?

Caesarian delivery....uterus...polymicrobial including staph and strept

19

What is the most common culprit for VIRAL ENCEPHALITIS? Which region of the brain is most commonly affected? WHAT is the TX??

Herpes Simplex Virus (Esp HSV-1!! WHEELHOUSE)..Temporal Lobe...TX=IV acyclovir

20

What group of viruses cause BUNYAVIRUS encephalitis?

California encephalitis group of viruses (mosquitoes)

21

What causes the chronic encephalitis known as subacute sclerosing PANenchephalitis?

measles!

22

What group of viruses does mumps and measles fall into?

PARAmyxOviridae

23

What is the culprit for RING-enhancing brain lesions in HIV patients??

TOXOPLASMA

24

What is a common fungal organism that can cause encephalitis in HIV patients?

Cryptococcus

25

Which PROTOZOA is NOTORIOUS for causing fatal encephalitis in AIDS patients?

A-CANTH-AMOEBA

26

ACUTE INTERMITTENT PORPHYRIA is caused by a genetic defect in the making of ________ and it characterized by WHAT MAJOR INDICATOR??

PBG (Porpho-Bilinogen) Deaminase

27

What is the telling factor when diagnosing between PCT (porphyria cutanea tarda) and AIP (acute intermittent porphyia)?

PCT=skin manefestations...AIP no skin manefestations

28

What is the most common NUTRITIONAL DEFICIENCY in elderly alcoholics?

COBALAMIN (vit B12)

29

What is an ACUTE postinfectious polyneuropathy characterized by nonspecific prodromal malaise and nausea followed by progressive, ascending paralysis?

GULLIAN-BARRE syndrome

30

HUH...WHEELHOUSE. Pt complains of difficulty chewing and diplopia...Whats he got? lol

Thymoma (MYASTHENIA GRAVIS) (60-70% have hyperplastic thymic tissue, 10-15% have thymomas)