Flashcards in Path Deck (148)
What is characterized by the development of hypoxemia and bilateral pulmonary infiltrates in the ABSENCE of heart failure??
ARDS-Acute Respiratory Distress Syndrome
What is a Kimmelsteil-Wilson lesion associated with? **Nodular** (mesangial expansion, glomerular basement membrane thickening, and glomerular sclerosis)
What is the bone tumor most often associated with Paget's Disease?
What are fragile mucosal folds that cause solid food dysphagia, usually in the mid to lower esophagus? What deficiency (Plummer-Vinson Syndrome) is it commonly seen?
Histologically, what are these signs pointing to? acute inflammatory monoarthritis, neutrophilic effusion, and numerous needle-shaped crystals?
What is the most common location for an endometrial cyst?
Which vitamin supplementation is NOT advised during pregnancy?
Vitamin A..it can be teratogenic in excess!
MOST follicular __ ____ _______ are associated with a t(14;18) translocation that leads to BCL2 over expression (BCL2 overexp=evasion of apoptosis)
B cell lymphomas
What disease is characterized by AUER bodies and is a t(15;17) chromosomal translocation?
APL-Acute Promyelocytic Leukemia
Which disease is associated with a t(8;14) translocation and classically has round nuclei, basophillic cytoplasm, and prominiant lipid vacuoles?
What is characteristic of a t(9;22) translocation and shows leukocytosis with many immature myeloid cells?
CHRONIC myeloGenous leukemia
What is the MOST COMMON translocation in childhood B-cell ACUTE LYMPHOCYTIC LEUKEMIA? (Peripheral blood smear=anemia, thrombocytopenia, and lymphoblasts)
What form of leukemia am I? malignant cells with notches or clefts and a t(14;18) translocation?
Which viral infection is associated with ballooning multinucleated giant cells?
Which carcinoma presents with cells at the periphery displaying parallel alignment (palisading)?
basal cell carcinoma
Which infection shows histologically with perinuclear HALOS?
Get ready for a new one...What is associated with umbilicated, flesh-colored papules on the skin and mucous membranes? Uh..WHATS ITS CAUSAL AGENT???
Molluscum Contagiosum (wtf?)...poxvirus
What is the most important risk factor for postpartum endometriosis? What organ? What bugs?
Caesarian delivery....uterus...polymicrobial including staph and strept
What is the most common culprit for VIRAL ENCEPHALITIS? Which region of the brain is most commonly affected? WHAT is the TX??
Herpes Simplex Virus (Esp HSV-1!! WHEELHOUSE)..Temporal Lobe...TX=IV acyclovir
What group of viruses cause BUNYAVIRUS encephalitis?
California encephalitis group of viruses (mosquitoes)
What causes the chronic encephalitis known as subacute sclerosing PANenchephalitis?
What group of viruses does mumps and measles fall into?
What is the culprit for RING-enhancing brain lesions in HIV patients??
What is a common fungal organism that can cause encephalitis in HIV patients?
Which PROTOZOA is NOTORIOUS for causing fatal encephalitis in AIDS patients?
ACUTE INTERMITTENT PORPHYRIA is caused by a genetic defect in the making of ________ and it characterized by WHAT MAJOR INDICATOR??
PBG (Porpho-Bilinogen) Deaminase
What is the telling factor when diagnosing between PCT (porphyria cutanea tarda) and AIP (acute intermittent porphyia)?
PCT=skin manefestations...AIP no skin manefestations
What is the most common NUTRITIONAL DEFICIENCY in elderly alcoholics?
COBALAMIN (vit B12)
What is an ACUTE postinfectious polyneuropathy characterized by nonspecific prodromal malaise and nausea followed by progressive, ascending paralysis?