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Flashcards in Micro Associations Deck (76):
1

Tumbling motility, grows in cold, β-hemolytics

Listeria - meningitis in babies, unpasteurized milk

2

Gastroenteritis from mayo?

Staph aureus

3

Where does Staph Aureus colonize?

Nose

4

Adherent biofilms

Staph epidermidis

5

Hepetization of lung during pneumonia?

Strep. pneumo

6

Rusty sputum and sepsis in sickle cell/spenectomy

Strep pneumo

7

Lancet-shaped, G+ diplococci

Strep pneumo

8

S. sanguinis makes dextrans which allows for ___________.

Endocarditis (viridins group)
Binds to fibrin-platelet aggregates

9

Strep pharyngitis

PHever or glomerulonePHritis

10

Scarlet fever

Strawberry tongue
Scarlet sandpaper rash
Circumoral pallor

11

Hippurate test +

Group B strep - screen women at 35-37 weeks
Intrapartum penicillin prophylaxis

12

Metachromatic blue and red granules + Gram Positive rods

C. diptheriae

13

How do you kill spores?

Autoclave - steam at 121˚C for 15 min

14

What bugs form spores?

B. anthracis
C. perfringens
C. tetani & botulinum
B. cereus
Coxiella burnetti

15

What toxins does C. Diff produce

Toxin A - destroys brush border enzymes
Toxin B - depolymerizes actin

16

What is the only bacterum with a polypeptide capsule w/ D-glutamate

Bacillus anthracis

17

What causes gastroenteritis from rice/pasta?

B cereus - cereulide

18

Tumbling motility, deli meats and unpasteurized milk

Listeria

19

What is the only Gram Positive to produce LPS?

Listeria

20

Where is Nocardia found? What infections does it cause?

Soil - pulmonary infections in IC and cutaneous infections post trauma in IC

21

What are the branching filamentous G+ bugs?

Nocardia
Actinomyces

22

What do you give AIDS patients for MAC prophylaxis?

Azithromycin

23

What is the reservoir in the US for M leprae?

Armadillos

24

What bug has cord factor and sulfatides?

Mycobacterium tuberculosis
CF = block Mφ maturation and induces release of TNF-α
Sulfatides = inhibit phagolysosomal fusion

25

Pasteurella

Animal bites

26

How do you treat Neisseria?

Ceftriaxone

27

What drugs do you use for prophylaxis of Meningitis (neisseria) in close contacts?

Ceftriaxone
Cipro
Rifampin

28

What 2 diseases does legionella cause?

Pontiac fever = mild flu
Legionnaires = severe pneumonia
Treat w/ Macrolide or quinolone

29

What 2 toxins does pseudomonas have?

Endotoxin - fever/shock
Exotoxin A - inactivates EF2

30

What causes hot tub folliculitis?

Pseudomonas

31

What causes malignant otitis externa in diabetics?

Pseudomonas

32

What cuases chronic pneumonia in CF patients?

Pseudomonas (biofilm)

33

What 4 diseases does Klebsiella cause?

Aspiration pneumonia
Pneumonia in diabetics
Abscess in lung/liver

34

Mucoid colonies

Klebsiella - abundant polysaccharide capsules

35

Red currant jelly sputum?

Klebsiella

36

What are the 4 types of E. coli?

EIEC - invasive, dysentary
ETEC - toxins - travelers diarrhea
EPEC - pediatric diarrhea
EHEC - Shiga-like toxin - HUS

37

What e. coli doesn't ferment sorbitol?

EHEC

38

What GN rod doesn't ferment lactose, invades the intestinal mucosa and causes a monocytic response?

Salmonella

39

What GN rod doesn't ferment lactose, invades the intestinal mucosa and causes a PMN infiltration?

Shigella

40

How does campylobacter jejuni get transmitted?

Fecal/oral
Poultry, meat, unpasteurized milk
GBS and Reactive Arthritis

41

Pet feces, contaminated milk/pork - mimics Crohns or appendicitis

Yersinia

42

What is triple therapy for H. pylori?

PPI + Clarithromycin + Metro/Amoxicillin
**No metro in alcoholics**

43

Water contaminated with animal urine?

Leptospira - Flu-like, jaundice, photophobia
*surfers, tropics

44

Ixodes tick

Borrelia burgdorferi (Lyme Disease)

45

What are the 4 main signs of Lyme disease

Facial nerve palsy
Arthritis
Kardiac block
Erythema migrans
*Ceftriaxone/Doxy*

46

How do you screen for syphilis? Confirm?

VDRL/RPR - non-specific
FTA-ABS

47

Saber shins, saddle nose, CN VIII deafness, Hutchinson teeth, mulberry molars?

Congenital syphilis

48

How do you prevent congenital syphilis?

Treat mother early in pregnancy - placental transmission occurs after 1st trimester

49

VDRL false positives

Viruses - mono, hepatitis
Drugs
Rheumatic Fever
Lupus/Leprosy

50

Jarisch-Herxheimer reaction

Flu-like syndrome after antibiotics started - killed bacteria release pyrogens

51

Grey vaginal discharge w/ fishy smell - nonpainful

Gardenerella vaginosis
Metro or Clindamycin

52

Rickettsiae are obligate intracellular because they need what 2 things?

CoA and NAD+
*Can't synthesize ATP*

53

What 3 diseases do you see a palms and soles rash?

Coxsackievirus A
Rocky Mountain spotted fever
2˚ Syphilis

54

Rickettsia typhi

Typhus (fleas)
rash on trunk - spares palms/soles

55

Rocky Mountain Spotted Fever

Rickettsia rickettsii (tick) Rash at wrists and ankles and spreads

56

Bird/Bat droppings

Histoplasmosis - hides in Mφ
Pneumonia

57

Blastomycosis

Inflammatory lung disease - skin and bone
Granulomatous nodules
Broad budding base (=RBC)

58

Erythema nodosum and arthralgias associated with dust/dirt in SW US

Coccidioidomycosis - skin and bone
Spherules filled with endospores - large

59

Captains wheel formation

Paracoccidioidomycosis
Latin America
Very large budding yeast (>>RBC)

60

How do you treat the systemic mycoses?

Histo/Blasto/Coccidioides
Azole = local infection
Amphotericin B = systemic

61

Granuloma formation in the lung that appears like TB could also be what?

Systemic mycoses: histo/blast/coccid
**No person-person transmission

62

Sphaghetti and meatball appearance

Malassezia furfur
Miconazole or selenium sulfide
Hypo/hyperpigmented patches

63

Healthcare provider

HBV (needlestick)

64

Organ transplant recipient

CMV

65

Neutropenic patients

Candida (systemic), Aspergilus

66

Pneumonia in CF, burn infection

Pseudomonas

67

Sepsis/meningitis in newborn

Group B strep

68

Surgical wound

S. aureus

69

Traumatic open wound

C. perfringens

70

Pus, empyema, abscess

S. aureus

71

UTI culture with swarming on agar, urease +, struvite stones

Proteus

72

Vaginal infections with inflammation, white cottage cheese discharge, normal pH

Candida

73

Viral meningitis

Enterovirus (Coxsackievirus)

74

What is the main characteristic of Shigella causing disease?

Invasive - M cells

75

What is the dominant microorganism in the colon?

B. fragilis > E. coli

76

Post viral causes of pneumonia

Staph, H flu, S pneumo