Toxins and Antidotes Flashcards Preview

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Flashcards in Toxins and Antidotes Deck (21):
1

Acetaminophen

N-acetylcysteine - replenishes glutathione

2

AChE inhibitors/organophosphates

Atropine + pralidoxime

3

Amphetamines (basic)

NH4Cl - acidify urine

4

Antimuscarinic/anti-cholinergic agents

Physostigmine salicylate, control hyperthermia

5

Benzodiazepines

Flumazenil

6

β-blockers

Glucagon

7

Carbon monoxide

100% O2

8

Copper, arsenic, gold

Penicillamine

9

Cyanide

Nitrate + Thiosulfate, hydroxocobalamin

10

Digitalis

Anti-dig Fab fragments

11

Heparin

Protamine sulfate

12

Iron

Deferoxamine, deferasirox

13

Lead

EDTA, dimercaprol, succimer, penicillamine

14

Mercury, arsenic, gold

Dimercaprol (BAL), succimer

15

Methanol, ethylene glycol

Fomepizole > ethanol, dialysis

16

Methemoglobin

Methylene blue, vitamin C

17

Opioids

Naloxone

18

Salicylates

NaHCO3 (alkalinize urine), dialysis

19

TCAs

NaHCO3 (plasma alkalization)

20

tPA, streptokinase, urokinase

Aminocaproic acid

21

Warfarin

Vitamin K, FFP (if bleeding)