Micro: Fungal and Parasites Flashcards Preview

Respiratory Exam 2 > Micro: Fungal and Parasites > Flashcards

Flashcards in Micro: Fungal and Parasites Deck (24):
1

Name the 4 dimorph fungi.

Can Have Both Shapes
-Coccidiodes
-Histoplasma
-Blastomyces
-Sporothrix

2

How are the dimorphs differentiated from one another?

unique characteristics of yeast form.
(respiratory symptoms are very similar between all dimorphs)

3

Geography of Coccidiodes immitis.

Desert Southwest of U.S.

4

Characteristic yeast form of C. immitis.

Spherule

5

What lab test differentiates fungi and parasites from other microbes?

KOH prep

6

Treatments and MOA for fungal infections.

Azoles (Fluconazole) is primary medication
-prevents synthesis of ergosterol

Amphotercin B: used in severe acute cases and pregnant patients because azoles are Teratogenic
-targets ergosterol creating a pore in the cell wall of fungal cells

7

Characteric yeast form of Blastomyces dermatitidis.

Broad Based Budding yeast

8

Pathogenesis of Histoplasma capsulatum.

Intracellular yeast: infects macrophages and plasma cells

9

Source of Histoplasma.

Bird and bat dung
-spelunking in caves

10

"Pilot's Wheel" budding yeast.

Paracoccidiodomycosis
(Paracoccidiodes brasiliensis)

11

Acute Angle budding hyphae in yeast

Aspergillus sp.

12

Presentation of a patient with Farmer's Lung and Tx.

Dry cough and chest tightness that occurs over and over again. Symptoms regress when taken away from offending agent. Alergic Aspergillosis sp. is a common cause.

Tx: for any Allergic Aspergillosis use oral corticosteroids

13

Pathogenesis and Tx for Non-invasive Aspergillosis.

Fungus grows in a cavity in the lungs (fungal ball or aspergilloma). Only occurs after some other disease has occurred: TB, CF, chronic bronchitis.

Tx: surgical excision

14

Risk factors for invasive Aspergillosis.

IC patients: transplant, leukemia, lymphoma, AIDS, corticosteroid therapy.

15

Tx for invasive Aspergillosis

Voriconazole

16

Disease caused by Zygomycosis sp. and characteristic of yeast for diagnosis.

Mucor
-90 degree branched hyphae

17

Population most at risk for Mucor and unique clinical presentation.

Ketoacidotic Diabetics
-black pus from eyes, nose, and mouth

18

Tx for Mucor.

Amphotercin B

19

#1 AIDS associated infection.

Pneumocystis jiroveci
-presents as atypical pneumonia

20

How does Pneumocystis appear on Giemsa stain microscopy?

Dented Helmets

21

Only lung parasite we need to know.

Paragonimus westermani (Lung Fluke)

22

Intermediate host of the lung fluke.

Snail

23

Presenting respiratory symptoms of lung fluke.

Rust colored sputum (or coffee ground sputum)
-often mistaken for TB

24

How can a lung fluke be differentiated from TB?

Eggs found in sputum