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Flashcards in Pulmonary TB Deck (13):
1

What is a Ghon lesion?

Calcified parenchymal focus (granuloma). Later stage of granuloma in TB disease progression.

2

What is a Ranke Complex?

AKA Ghon Complex
It is a Ghon lesion (calcified granuloma) plus infected hilar lymph nodes

3

Type of Hypersensitivity rxn of a positive PPD (purified protein derivative test)

Type IV

4

When assessing a positive PPD test, a papule that is at or greater than 5mm in diameter should be considered a (+) TB infection for which populations?

HIV pts
Close contact with infected pts
IC pts

5

When assessing a positive PPD test, a papule that is at or greater than 10mm in diameter should be considered a (+) TB infection for which populations?

People with clinical conditions that are not considered IC conditions

Cancers

Children younger than 4

Workers and inmates at prisons, workers in micro labs, homeless

People born in endemic areas

6

When assessing a positive PPD test, a papule that is at or greater than 15mm in diameter should be considered a (+) TB infection for which populations?

Healthy people with no risk factors

7

Gold standard for definitive TB diagnosis.

Sputum culture (acid fast)

8

How does the INF-gamma assay test for TB?

Take a patient's blood and expose it to TB.
1. measure the INF-gamma levels released by T cells
2. Higher levels indicate a strong T cell response meaning that the patient has been exposed to TB

9

What is the first precaution taken with patients confirmed to be infected with TB?

Isolation
-N95 mask
-negative pressure room

10

What is the combo medication regimen for active TB patients?

RIPE
Rifampin
Isoniazid
Pyrazinamide
Ethambutol
-Tx normally lasts 6 months

11

How are HIV patients treated for TB infection?

Same as non-HIV individuals

12

What is the treatment for latent TB

Isoniazid for 9 months
or
Rifampin for 4 months

13

Biggest complication of miliary TB

Spread to multiple organ systems