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Flashcards in Microbiology - Systems Deck (18):
1

ToRCHeS

microbes that may passed from mother to fetus
- mostly transplacental or via delivery (e.g. HSV-2)
- often present with hepatosplenomegaly, jaundice, thrombocytopenia, and growth retardation

2

Toxoplasmoa gonddi

- transmitted by cat deces or ingestion of undercooked meat
- mother presentation: asymptomatic
- baby presentation: chorioretinits, hydrocephalus, and intracranial calcifications

3

Rubella

- transmitted via respiratory droplets
- maternal: rash, lymphadenopathy, arthritis
- neonatal: PDA (or pulmonary hypoplasia), cataracts, deafness +/ blueberry muffin rash

4

CMV

- transmitted via sexual contact, organ transplant
- maternal: mono-like illness, asymptomatic
- baby: hearing loss, seizures, petechial rash, blueberry muffin-rash

5

HIV

- transmitted via sexual contact, needlestick
- maternal: variable depending on CD4
- baby: recurrent infections, chronic diarrhea

6

HSV-2

- transmitted by skin or mucous membrane contact
- maternal: usually asymptomatic, herpetic lesions
- baby: encephalitis, herpetic lesions

7

Syphilis

- transmitted by sexual contact
- maternal: chancre (primary) and disseminated rash (secondary_
- baby: still birth, hydrops fetals. if child survives, facial abnormalities, saddle nose, short maxila, saber shings, CN VIII deafness

8

Red rashes of childhood

-Rubella
- Measles
- VZV
- HHV-6 (Roseola)
- Parvovirus (Erythema infectiosum)
- Scarlet fever (Group A Strep)
- Hand-foot-mouth disease (Coxsackie virus)

9

Bugs in unimmunized children

- Rubella
- Measles
- Meningitis
- Pharyngitis
- Epiglotti

10

Rash in unimmunized child that begins at head and moves down with posterior auricular lymphadenopathy

Rubella

11

Rash in unimmunized child/immigrantthat begins at head and movess down.
Rash preceded by cough, coryza (rhinitis), conjunctivitis, and blue-white spots on buccal mucosa

Measles

12

Meningitis in unimmunized child/immigrant
Colonizes nasopharynx

H. influenzae b

13

Meningitis in unimmunized child/immigrant
- leads to myalgia and paralysis

Poliomyelitis

14

Pharyngitis in unimmunized child/immigrant with grayish oropharyngeal exudate
("pseudomembranes) that may obstruct airway

C. diptheriae
- elaborates toxin that causes necrosis in pharynx, cardiac, and CNS tissue

15

Epiglottitis in unimmunized child/immigrant. Has fever with dysphagia, drooling, difficulty breathing due to edematous "cherry red" epiglottis

H. influenzae

16

CSF findings in bacterial meningitis

- Elevated opening pressure
- Elevated PMNs
- Elevated proteins
- Decreased sugar

17

CSF findings in fungal/RB meningitis

- Elevated opening pressure
- Elevated lymphocytes
- Elevated proteins
- Decreased sugar

18

CSF findings in viral meningits

- Normal/elevated opening pressure
- Elevated lymphocytes
- Normal/elevated protein
- Normal sugar