Microbiology - Zoonotic Bacteria Flashcards Preview

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Flashcards in Microbiology - Zoonotic Bacteria Deck (41):
1

Bartonella spp

- Cat scratch disease
- transmitted by cat scratch

2

Borrelia burgdoferi

- Lyme disease
- transmitted by Ixodes tick (liver on deer and mice)

3

Borrelia recurrentis

- Recurrent fever
- transmitted by louse (recurrent due to variable surface antigens)

4

Brucella spp

Brucellosis/ undulent fever
- transmitted by unpasteurized dairy (e.g. goat cheese/milk)

5

Campylobacter

- Bloody diarrhea
- transmitted by puppies, livestock (fecal-oral, ingestion of undercooked meat)

6

Chamydophila psittaci

Pstitacosis ("bird with clam shell sitting on skin)
- transmitted by parrots or other birds

7

Coxiella burnetti

Q fever
- aerosols of cattle/sheep amniotic fluid

8

Ehrlichia chaffeensis

Ehrlichiosis
- transmitted by Lone Star Tick

9

Francisella tularensis

Tularemia (site specific infection + lymphadenopathy)
- transmitted by ticks, rabbits, deer fly

10

Leptospira spp

Leptospirosis
- transmitted by animal urine

11

Mycobacterium leprae

Leprosy
- transmitted by armadillos and humans with lepromatous leprosy

12

Pasteurella multocida

Cellulitis, Osteomyelitis
- transmitted by animal bite, cat, dogs

13

Ricksettia prowazekii

Endemic typhus
-transmitted by louse

14

Ricksettia ricksetti

Rocky Mountain Spotted Fever
- transmitted by Dermacentor tick bite

15

Ricksettia typhi

Endemic typhus
- transmitted by fleasq

16

Yersinia pestis

Plague (fever, dark skin patches, regional lymphadenopathy)
-transmitted by fleas (rats and prairie dogs are reservoirs)

17

Gardenerella vaginalis

Pleomorphic gram-variable rod causes vaginosis
- gray vaginal discharge with fishy smell, non-painful
- associated with sexual activity, but not STD
- characterized by overgrowth of certain bacteria
- Clue cells or vaginal epithelial cells covered iwth bacteria

18

Tx for Gardenerella vaginalis

Metronidazole

19

Treatment for all rickettsial disease

Doxycycline

20

Rocky Mountain Spotted Fever

- caused by Rickettsia rickettsii
- found broadly in US
- RASH typically starts at wrists and ankles and then spread s to trunk, palms, and soles.

21

Rickettsiae

- obligate intracellular organisms that need CoA and NAD+

22

Palm and sole rashes are seen in which disease?

"you drive CARS using your 'palms' and 'soles'"

Coxsackievirus
A infection (hand, foot, and mouth disease)
Rocky Mountain Spotted Dever
Syphillis

23

Ehrlichiosis

- tick borne disease
- monocytes with morula (berry-like inclusions) in cytoplasm
- NO RASH

24

Anaplasmosis

-tick borne disease
Granulocytes with morula in cytoplasm
- NO RASH

25

Q fever

- caused by Coxiella burnetti
- transmitted by tick feces and cattle placenta release spores that are inhaled as aerosols

- Present as pneumonia (NO RASH)

26

Chlamydiae

cannot make their own ATP
obligate intracellular organims tha cause mucosal infections

27

Lab diagnosis of Chlamydiae:

Cytoplasmic inclusions seen on Giemsa or fluorescent antbody-stained smear.

28

Feature unusual about chlamydiae cell wall

Lacks muramic acid

29

Two forms of chalmydiae

Elementary body
Reticulate body

30

Elementary body (chlamydiae)

- infectious and enters cell via endocytosis

31

Reticulate body (chlamydiae)

- replicates in cell by FISSION; forms seen on tissue culture

32

Chlamydiae trachomatis

- causes reactive arthritis, conjunctivitis, nongonococcal urethritis, and PID

33

C. pneumoniae and C. psittaci

- cause atypical pneumonia
- transmitted by azithromycin

34

Treatment of Chlamydiae

Azithromycin (favored because one time treatment) or doxycycline

35

Chlamydia trachomatis serotype: A, B, and C

Chronic infection, cause blindness due to follicular conjunctivitis in Africa

ABC = Africa/Blindness/Chronic Infection

36

Chlamydia trachomatic serotype: D-K

Urethritis/PID, ectopic pregnancy, neonatal pneumonia (stacatto cough), or neonatal conjunctivitis

37

C. trachomatis serotype: L1, L2, and L3

Lymphogranuloma venereum - starts as painless sore and then migrates to lymph nodes

38

Mycoplasma pneumoniae

Classic cause of "walking" pneumonia
(insiduous onset, headache, nonproductive cough, diffuse interstitial infiltrate)

X ray: looks worse than patient

High titer of COLD agglutinins (IgM), which can agglutinate or lyse RBCs. Grown on Eaton's agar

39

Treatment of Mycoplasma pneumoniae

Macrolide or or Fluoroquiniolone (penicillin ineffective since Mycoplasma hae no cell wall)

40

Fx unusual about Mycoplasma pneumoniae

No cell wall. Not seen on Gram stain
Bacterial wall contains sterols for stability

41

Mycoplasma pneumoniae - popular in what population

"Walking pneumoniae" in patients < 30 years old
- Frequent outbreaks in military recruits and prisons