Renal - Stuff Missed Flashcards Preview

USMLE Step 1 > Renal - Stuff Missed > Flashcards

Flashcards in Renal - Stuff Missed Deck (14):
1

Renal handling of PAH

- always more is secreted than filtered

2

Renal handling of Inulin

- is neither reabsorbed or secreted by kidneys

3

Renal handling of sodium

- > 99% of filtered Na is reabsorbed
- <1% is excreted

4

Renal handling of urea

- at fixed GFR, 40 - 50% of filtered urea is reabsorbed by proximal tubule

5

Renal handling of glucose

at low plasma concentration, it is completely reabsorbed
at high plasma concentrations, it increased fractional excretion is observed

6

How does Ureteral constriction or obstruction affects GFR and filtration fraction

- Decreases GFR and decreases filtration fraction

7

Filtration Fraction formula

GFR/RPF

8

Rheumatic fever

autoimmune reaction following untreated Group A Strep (Strep pyogenes)
- antigenic similarity between bacterial antigens and normal "self" antigents in heart and CNS cause formation of anti-self antibodies

9

Familial hypercholesteremia

AD
underexpression of LDL receptors leads to accelerated atherosclerosis and early-onset CAD

10

Resistance of vessels in parallel

1/R(total) = 1/(R1) +1/(R2) + 1/(R3) +....

11

Signs of microembolisms

Janeway lesions (nontender lesions on palms and soles)
- Splinter hemorhages - streaks on nail bead

12

Side effects of niacin (esp. in relation to hypertensive and diabetes medications)

- Can potentiate anti-hypertensive medications due to vasodilatory effects
- Can cause insulin resistance and may necessitate increase in diabetes medications

13

Varicose veins

due to prolonged increases in intraluminal pressure and loss of vessel wall tensile strentch
- due to incompetent venous valves, venous stasis, edema

14

Phlegmasia alba dolens

consequence of ilofemoral venous thrombosis