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USMLE Step 1 > Pathology Images > Flashcards

Flashcards in Pathology Images Deck (7)
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1
Q

Sx: 59 y.o Japanese presents with recent weight loss, epigastric discomfort afer meals, and occasional nausea

A

Diffuse Stomach Cancer

  • Notice the signet ring cells
  • Infiltrates the stomach wall with mass composed of glandular cuboidal and columnar cells
2
Q

Cavernous hemangioma

A
  • most common benign liver tumor

  • typically presents in adults 30-50 years old
  • tumors consist of cavernous, blood-filled spaces lined by single epithelial layer
  • Most patient are assymptomatic but may experience RUQ fullness

Tx: Surgical ressection (Excellent prognosis)

3
Q

Peripheral Smear of Patient with Glucose 6 Dehydrogenase Deficiency

A
  • RBCs contain Heinz bodies (intracellular inclusions with denatured Hb)
  • May contain Bite cells due to splenic macrophages removing Heinz bodies
4
Q

Squamous Cell Carcinoma (of Esophagus)

A
  • presents with progressive dysphagia as tumor gradually obstructs lumen
  • Risk factors: smoking and chronic alcohol use
  • KERATIN PEARLS AND INTERCELLULAR BRIDGES
5
Q

Reflux Esophagitis

A
  • Commonly occurs during GERD

Note: Elongation of papillae, basal cell hypertrophy, and intraepithelial eosinophils

  • Repeated epithelial injury can lead to intestinal metaplasia (Barrett’s esophagus) - where spamous epithellum is transformed to columnar epithelium
6
Q

Leiomyomas

A

Benign tumors of esophagus that are rare and slow-growing.

Light microscopy: consist of fasciles of spindle cells with variable amounts of fibrosis

7
Q

Echinococcus granylosus

A

most common cause of hydatid cysts

occur in endemic areas in Middle East, southern South America, Iceland, Oceania

intial infection is assymptomatic

Liver is affected first, but can affect lung, muscle, or bone

cysts have “eggshell calcification” and are encapsulated that contain fluid and budding cells that will become daughter cells

** ASPIRATION is inadvisable**