Minimum Alveolar Concentration: A Measure of Potency Flashcards Preview

Apex 4 - 5 Volatile Anesthetics II: Pharmacodynamics (11) > Minimum Alveolar Concentration: A Measure of Potency > Flashcards

Flashcards in Minimum Alveolar Concentration: A Measure of Potency Deck (33)
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1

Order the volatile anesthetics from lowest to highest potency. (One is the least potent and four is the most potent)

Study on!!!!

2

The concentration of inhalational anesthetic that prevents the nociceptive withdrawal reflex following a supramaximal painful stimulus in 50 percent of the population is otherwise known as:

Minimum Alveolar Concentration (MAC)

3

Minimum alveolar concentration (MAC) is the concentration of inhalational anesthetic that prevents the nociceptive withdrawal reflex following a supramaximal painful stimulus in 50 percent of the population. Remember that this is in the ----- midazolam, fentanyl, propofol, etc.

"absence of residual"

4

MAC is a measure of -----. It is akin to the ED50

Potency

5

What's the MAC of Isoflurane for a 40 Year Old (%)

1.2%

6

What's the Relative Potency of Isoflurane?

++++

7

What's the MAC of Sevoflurane for a 40-Year-Old (%)?

2.0 %

8

What's the Relative Potency of Sevoflurane?

+++

9

What's the MAC of Desflurane for a 40-Year-Old (%)?

6.6%

10

What's the Relative Potency of Desflurane?

++

11

What's the MAC of Nitrous Oxide for a 40-Year-Old (%)?

104%

12

What's the Relative Potency of Desflurane?

+

13

The essential triad of anesthetic action includes:

  1. Amnesia
  2. Loss of consciousness
  3. Immobility

14

Amnesia is a component of the essential triad of anesthetic action

 

 

True

15

Loss of consciousness is a component of the essential triad of anesthetic action

 

 

 

True

16

Immobility is a component of the essential triad of anesthetic action

 

 

 

True

17

Volatile agents also modulate autonomic function and may provide some -----.

Analgesia

18

The essential triad of anesthetic action includes Amnesia, Loss of consciousness, & Immobility. These effects are ----- dependent

Dose-dependent

19

The essential triad of anesthetic action includes Amnesia, Loss of consciousness, & Immobility. These effects are dose-dependent. For example, supraspinal effects such as amnesia and loss of consciousness  occur at ----- concentrations

Lower concentrations

20

The essential triad of anesthetic action includes Amnesia, Loss of consciousness, & Immobility. These effects are dose-dependent. For example, supraspinal effects such as amnesia and loss of consciousness occur at lower concentrations, while immobility requires a -----concentration

Higher concentration

21

The essential triad of anesthetic action includes Amnesia, Loss of consciousness, & Immobility. These effects are dose-dependent. For example, supraspinal effects such as amnesia and loss of consciousness occur at lower concentrations, while immobility requires a higher concentration. This suggests anesthetics exert these effects in ----- regions of the CNS

"different"

22

MAC is additive

0.5 MAC isoflurane + 0.5 MAC N2O =

1 MAC

23

MAC ----- is the alveolar concentration at which a patient opens his or her eyes

MAC-awake

24

MAC-awake is the alveolar concentration at which a patient opens his or her eyes. This shows hysteresis in that MAC-awake is ~ --- to --- during induction
 

~ 0.4 - 0.5 MAC

25

MAC-awake is the alveolar concentration at which a patient opens his or her eyes. This shows hysteresis in that MAC-awake is ~ 0.4 - 0.5 during induction, but during recovery MAC- awake is as low as --- MAC

0.15 MAC

26

MAC ----- is the alveolar concentration required to block the autonomic response following a supramaximal painful stimulus

 

MAC-bar

27

MAC-bar is the alveolar concentration required to block the autonomic response following a supramaximal painful stimulus. MAC-bar = ~ --- MAC

1.5 MAC

28

Movement can be prevented in 95 percent of the population at ~ --- MAC

1.3 MAC

29

Awareness and recall is generally assumed to be prevented at --- to --- MAC

0.4 - 0.5 MAC

30

Order the volatile anesthetics from lowest to highest potency. (One is the least potent and four is the most potent)

Nitrous oxide + 1 (least potent)

Desflurane + 2

Sevoflurane  + 3

lsoflurane + 4 (most potent)