Nitrous Oxide: Peculiarities Flashcards Preview

Apex 4 - 5 Volatile Anesthetics II: Pharmacodynamics (11) > Nitrous Oxide: Peculiarities > Flashcards

Flashcards in Nitrous Oxide: Peculiarities Deck (75)
Loading flashcards...
1

What is the blood: gas partition coefficient of nitrogen?

Study on!!!

2

How Nitrous Oxide Affects Closed Air Spaces?

Let's find out!!!

3

Nitrous oxide is ~--- times more soluble than nitrogen

~34 times

4

Nitrous oxide is ~34 times more soluble than nitrogen. This means that for every 1 molecule of nitrogen that leaves a closed space, --- molecules of nitrous oxide enter to take its place

34 molecules

5

Nitrous oxide blood: gas partition coefficient =

0.46

6

Nitrogen blood: gas partition coefficient =

0.014

7

In a ----- airspace, nitrous oxide increases the volume of the space

"compliant"

8

In a compliant airspace, nitrous oxide increases the volume of the space. At some point, the compliant airspace will convert to a ----- airspace

"fixed"

9

In a compliant airspace, nitrous oxide increases the volume of the space. At some point, the compliant airspace will convert to a fixed airspace. In a fixed airspace, nitrous oxide increases the ----- of the space

Pressure

10

The rate of pressure change inside the space is dependent on:

 

Compliance of the space

Partial pressure of nitrous oxide

Perfusion of the surrounding tissue

Time

11

When N2O enters a space, the rate of pressure change inside the space is dependent on the ----- of the space

 

Compliance

12

When N2O enters a space, the rate of pressure change inside the space is dependent on the ----- of nitrous oxide

 

 

Partial pressure

13

When N2O enters a space, the rate of pressure change inside the space is dependent on the ----- of the surrounding tissue

 

 

 

Perfusion

14

When N2O enters a space, the rate of pressure change inside the space is dependent on Time

 

 

 

True

15

The rate of pressure change inside the space is dependent on the compliance of the space, the partial pressure of nitrous oxide, the perfusion of the surrounding tissue, and time. Knowing this allows you to predict the situations where nitrous is potentially -----.

"harmful"

16

N20 increases ----- in Compliant Airspaces

A. Volume

B. Pressure

Volume

17

N20 increases volume in Compliant Airspaces. This causes ----- or ---- Equilibration Between Space and Blood, depending on the space

 

Fast or Slow

18

N20 increases volume in Compliant Airspaces such as pulmonary -----. This causes Fast equilibration between space and Blood. 

Pulmonary Blebs

19

N20 increases volume in Compliant Airspaces such as air bubbles in the -----. This causes Fast equilibration between space and Blood. 

Blood

20

N20 increases volume in Compliant Airspaces such as ----- bubble in the eye. This causes Fast equilibration between space and Blood. 

Sulfa hexafluoride bubble

21

N20 increases volume in Compliant Airspaces such as the Bowel. This causes ----- equilibration between space and Blood

Slow

22

N20 increases volume in Compliant Airspaces such as the Pneumoperitoneum. This causes ----- equilibration between space and Blood. 

Slow

23

N20 increases ----- in Fixed Airspaces

Pressure

24

N20 increases Pressure in Fixed Airspaces. This causes ----- Equilibration Between Space and Blood

Fast Equilibration

25

N20 increases Pressure in Fixed Airspaces such as the Middle ear. This causes ----- Equilibration Between Space and Blood

"Fast"

26

N20 increases Pressure in Fixed Airspaces such as the Brain during intracranial procedures. This causes ----- Equilibration Between Space and Blood

"Fast"

27

Nitrous oxide quickly ----- middle ear pressure

 

"increases"

28

Nitrous oxide quickly increases middle ear pressure, which can ----- a tympanic membrane graft

 

"damage"

29

Conversely, discontinuation of nitrous oxide can quickly ----- middle ear pressure

 

"decrease"
 

30

Conversely, discontinuation of nitrous oxide can quickly decrease middle ear pressure and can result in -----.

Serous otitis