MOA

Question 1

inhibition of COX-2 near the site of application

Answer 1

diclofenac

Question 2

less effective but safer than NSAIDs

Answer 2

acetaminophen

Question 3

reserved for those who fail 1st line agents because opioids lack evidence for use w/ chronic pain

Answer 3

tramadol

Question 4

hydrocodone-APAP or oxycodone-APAP with risk of abuse

Answer 4

opioid analgesics

Question 5

dual reuptake inhibitor of both serotonin and NE leading to a possible lowered pain threshold

Answer 5

duloxitine

Question 6

deplete substance P

Answer 6

capsaicin, topical