MODULE 6 PART 2: DRUG DISTRIBUTION

Question 1

Compounds that pass rapidly, thru bet capillary endothelial cells, but do not penetrate other cells, are distributed into the ?

Answer 1

ECF spaces

Question 2

What are the physiological barriers with relevance to drug distribution?

Answer 2

1. BBB
2. Pial barrier
3. Placental barrier
4. Mammary gland barrier

Question 3

An extent to which a drug administered as a particular dosage form reach/enters the systemic circulation intact.

Answer 3

Bioavailability

Question 4

Rate of absorption is rated by the time at which it reach the ?

Answer 4

Peak plasma concentration