more MT stuff Flashcards
anti neutrophil plasmocytic auto antibodies are characteristic of what?
Type III Pauci-immune
What 3 diseases are found with type III pauci-immune?
IGA Nephropathy
Wegener’s Granulomatosus
Poly arteritis Nodosa
vasculitis of vessels with pouching of wall, does not affect the lungs or arch of the aorta
Poly arteritis Nodosa (incurable)
Melting of bones on face that lead to infection
necrotising vasculitis of URT and LRT
terrible smell
Wegener’s Granulematosus
IGA nephropathy aka
Berger’s disease
Usually boys in 20s
hemorrhagic vasculitis
4 syndromes
Henoch Schonlein Purpura (type II Nephritis)
What syndrome of Henoch Scholein Purpura reduces survival rate from 90-70%
Kidney syndrome
2 types of rapidly progressive crescentic Glomerulonephritis
type 1: Anti GBM/ type II HS (goodpasteur’s syndrome)
Type 2: Immune complex deposition/ type III HS
systemic lupus erythematos, henock schonin purpura
Kidney involvement with lupus happens with
UV radiation
Acute pyelonephritis is caused by antibodies against_____ that destroy the ______ wall and is curable with ______
Strep
Glomerular
Corticosteroids
______Cells like the arterioles of the kidney and have _____
endothelial cells
podocytes
hormones of the kidney
renin
erythropoeitin
prostaglandins
if BP drops to ____ then the juxtaglomerular cell will secrete _____
50mg
Renin
BP cascade
renin=>angiotensinogen=>Angiotensin I=>Angiotensin II
acute glomerulonephritis turns chronic in ___ % of children and ___% of adults
1% children
50% adults
what filters the blood
glomeruli
What types of hypersensitivity do the following have?
- Anti-GBM Glomerulonephritis
- circulating immune deposition
- Heyman’s glomerulo nephritis
- type II
- type III
- not a HS reaction
disorders have rapid and progressive dysuria and death w/ in weeks for months
rapidly progressive crescentic glomerulonephritis
subclinical arthritis with pain in joints _____ syndrome
henoch-schonein purpura (articular syndrome)
hemorrhagic inflammation of stomach and duodenal walls _____ syndrome
henoch-schonein purpura (abdominal syndrome)
subcutaneous hemorrhages in legs buttocks and abdomen _____ syndrome
henoch-schonein purpura (cutaneous syndrome)
abdominal, articular and cutaneous syndrome all have a ____% chance of survival reduced to ____% with kidney added
90%
70%
ANA antibody, involves skin, lungs, cerebral vessels, seriouis hypertension, stroke
lupus erythematous
Lupus is type __ rapid crescentic glomerulonephritis and ___ hypersensitiviy
II
III HS