Path final RA Flashcards

1
Q

granulation tissue associated with RA

A

Pannus

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2
Q

RA has both ______ and _____ degeneration

A

chemical, mechanical

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3
Q

Female to male ratio

A

4:1

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4
Q

RA etiology

A

unknown

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5
Q

nonsuppurative proliferative synovitis which in time leads to destruction of the articular cartilage and progressive disabling arthritis

A

RA

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6
Q

RAStarts as _____ arthritis in small joints in hands and feet.

A

symmetrical

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7
Q

RA usually starts on 1rst___ and___ (first symptoms) usually no____

A

pip, mcp

DIP

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8
Q

What kind of fluid is found inside the joints with RA

A

inflammatory exudate

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9
Q

inflammatory pattern

A

bad in morning, better as day goes on

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10
Q

Stiffness due to

A

accumulation of fluid

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11
Q

may decrease pain and chances of the joints being fused

A

physical activity

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12
Q

Rheumatoid hand

A

ulnar deviation of finders at MCP joints
Atrophy of intercostal and interossei muscles
inflammation of the wrist

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13
Q

TENOSYNOVITIS aka

A

ganglion

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14
Q

inflammation of tendon sheath-2 layers of fibrous tissue that surround tendons

A

TENOSYNOVITIS aka ganglion

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15
Q

caused by excess fluid production and cured by hydrocortisol

A

TENOSYNOVITIS aka ganglion

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16
Q

why should you never remove the ganglion that results from Tenosynovitis?

A

results in stenosing tendinitis

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17
Q

long term soft tissue inflammation will cause what?

A

bones in vicinity to lose density (osteopenia)

18
Q

osteopenia:due to _____ that cause activation of_____

A

cytokines, osteoclasts

19
Q

Causes decrease in articular contact

A

periarticular osteopenia (typical for any chronic inflammatory joint disease)

20
Q

med term without nerve interference.

A

subluxation

21
Q

no articulating bones with no joint function

22
Q

swan neck deformity

A

hyperextension of PIP and flexion of DIP

23
Q

calosities in the ____ can cause a deformity called _____

A

MTPs, Hammertoes

24
Q

only part of joint with blood supply

A

synovial membrane(also has lots of nociceptors)

25
Cartilage allows for _____ of joints
congruency
26
2 functions of synovial fluid
lubricates joint surfaces nourishes cartilage
27
types of joint pathologies
inflammatory degeneration metabolic
28
Genes associates with RA
HLA DR4, DR1 | human leukocyte antigen
29
how does panes (granulation tissue) affect the joint?
requires more and more room, but space is limited
30
periarticular osteopenia can lead to
subluxation:slipping of bone resulting to loss of joint.
31
hyper extension of DIP and hyper flexion of PIP
boutonniere's deformity
32
Hallux valgus
subluxation of first MTP joint in patients w/o joint pathology. MTP moves laterally due to ligament elasticity. (wearing high heels, female, overweight)
33
Bunion is a protective factor for
hallux valgus
34
normal amount of fluid in the knee
5ml
35
more than normal(5ml) of fluid in knee can result in
hypomobility
36
Never _____ knee joint that has too much fluid
move
37
how do you treat a joint with excess fluit
remove fluid or take anti-inflammatory drug
38
can't see hip or knee joint on X-ray
aseptic necrosis (due occlusion of blood supply)
39
how do you treat aseptic necrosis of hip joint?
replacement
40
Rheumatoid nodules in lungs with pneumonoconious
Kaplan's syndrome
41
RA before age 16
juvenile arthritis
42
possible complications of Juvenile RA
under developed jaw early closure of growth plates anatomical short leg destruction of dens (can kill them w/c1 adjustment)