MS51-57 Test Flashcards

(58 cards)

1
Q

4 main phases of cell cycle?

A

Mitotic (M phase)
G1
Synthesis (S phase
G2

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2
Q

what happens in M phase?

A

process of nuclear division

in which chromosomes are paired then divided creating two daughter cells through a 5 step process

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3
Q

5 steps of M phase?

A
prophase
metaphase
anaphase
telophase
cytokinesis
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4
Q

what happens in G1?

A

growth and activity

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5
Q

what happens in S phase?

A

DNA is replicated

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6
Q

what happens in G2?

A

continued growth and building of spindle fibers and centrioles

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7
Q

what are growth factors?

A

a protein boosting growth of a tissue

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8
Q

what are cyclins?

A

a protein that initiates Mitosis (M)

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9
Q

cells that don’t divide?

A

neurons
muscle cells
red blood cells

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10
Q

cells that often divide?

A

skin cells
intestinal tract lining cells
nail/hair cells

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11
Q

what are stem cells?

A

cells that can permanetly change into another type of cell

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12
Q

what are gametes?

A

sex cells, either eggs or sperm
contain half the # of normal chromosomes

when joined produce a full set

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13
Q

what is asexual reproduction?

A

does not require two organisms to produce offspring; offspring are identical to parents

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14
Q

what is sexual reproduction?

A

requires two multicellular organisms and the offspring have a 50/50 mix of alleles from both parents

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15
Q

kinds of asexual and who use it?

A

budding (lots of division at one site) yeast and coral

fragmentation (a piece of you becomes new) plants and sponges

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16
Q

kind of sexual and who use it?

A

bacterial conjugation; bacteria

meiosis 1/2;for gametes

mitosis; for growth/repair/ maintenance

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17
Q

what is interphase?

A

G1, S, G2

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18
Q

what is cytokinesis?

A

cytoplasmic division producing 2 daughter cells

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19
Q

what is Go?

A

a resting non-dividing cell that exited the cell cycle

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20
Q

how is the cell cycle controlled?

A

growth factors-> cyclins -> CDK’s

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21
Q

what stops the cell cycle?

A

abnormalities such as;
DNA damage
mistakes in DNA replication
mitotic spindle malfunctions

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22
Q

what happens if cell cycle continues through abnormalities?

A

can lead to cancer or other diseases

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23
Q

what is a mutation?

A

change in DNA sequence that can be passed on

can be silent

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24
Q

what can cause a mutation?

A

alteration of base DNA

destruction/introduction/moving of genes/chromosomes

25
what are tumor suppressor genes?
(AKA antioncogene) a cell that protects the cell from a step that leads to cancer
26
what is proto-oncogene?
a normal gene that when altered becomes oncogene which contributes to cancer some signal cell division or regulate apoptosis
27
what is P53?
a gene regulating apoptosis, suppresses tumors, regulates cell cycle, and stops cell division if there is damaged DNA
28
benign tumors?
non-cancerous | non-spreading
29
malignant tumors?
cancerous out of control cells | can invade other tissue which spreads and leads to metastasis
30
cancer facts?
40% of people diagnosed 200 types 30% due to tobacco 1 in 4 deaths by cancer
31
what is cancer?
characterized by tumors, which when one gains the ability to spread becomes cancer
32
what causes cancer?
mutations in genes controlling the cell cycle 10% of cancer is hereditary
33
what is stage 4 cancer?
spread of tumors from original site
34
how to grow from benign to malignant?
angiogenesis loss of cell adhesion loss of anchorage dependance
35
what are haploids?
1 set of chromosomes use meiosis called gametes
36
what are diploids?
2 sets of chromosomes use mitosis somatic cells
37
what is chromatin?
the material that composes chromosomes (except bacteria) | made of protein, DNA, and RNA
38
what is Histone Proteins?
package and order DNA | mainly in chromatin
39
what are chromosomes made of?
chromatin
40
vertebrates are usually?
diploid (1 mat. 1 pat.)
41
what are somatic cells?
(2n)body cells that build an individual
42
haploid cells?
gametes (n)
43
how many homologous pairs are in humans?
23
44
how many chromosomes are in humans? how many are autosomal (non-sex)
46 44
45
in gametes how many chromosomes? how many are autosomal?
23 22
46
what is Karyotype?
shows the # and physical appearance of chromosomes in a cell's nucleus
47
cytokinesis in animal and plant cells?
``` animal= cleavage furrow plant= cell plate ```
48
what are germ line cells?
sex cells
49
what is reduction division?
AKA meiosis; division of a germ cell into 4 gametes
50
what is a tetrad?
AKA bivalent; a pair of paternal and maternal chromosomes
51
what is crossing over?
process of exchanging portions of maternal and paternal chromosomes
52
what is radiation?
targeted radiation waves to prevent cell division in cancer
53
what is chemotherapy?
a cocktail of drugs targeting both cancer and healthy cells, killing them
54
meiosis?
nuclear division of germ line cells creating 4 daughter cells through reduction division (2n->n)
55
reduction division does what?
reduces 2n germ line cells to 1n gametes through separation of homologous pairs
56
end of meiosis 1?
2 haploid daughter cells
57
what is metastasis?
spread of cancer cells from a tumor
58
what is apoptosis?
programmed cell death