MSK growth and repair Flashcards

(102 cards)

1
Q

What is a ligament

A

Dense band of collagenous tissue spanning a joint
Connects bone to bone
Gives joint stability
Multiple at joint

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2
Q

What is the structure of a ligament?

A
Type 1 collagen fibres
Contain fibroblasts for communication
Contain sensory fibres (proprioception/stretch)
Have surface vesells
Are crimped allow for stretching
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3
Q

When does a ligament rupture occur?

A

When force exceeds strength of ligament

Either expected or unexpected

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4
Q

What are the types of ligament rupture?

A

Can be complete or incomplete

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5
Q

What are the side effects of a ligament rupture?

A

Pain
Stability loss
Proprioception loss in joint

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6
Q

How does the haemorrhage caused by ligament rupture heal?

A

Blood clot that is reabsorbed
The replaced with heavy cellular infiltrate
Has hypertrophic vascular response

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7
Q

What happens to the scar tissue produced by a ligament healing?

A

The disorganised connective tissue matrix becomes more ligament light
Although still has major differences in composition and function

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8
Q

How do you treat a ligament injury?

A

Conservative or operative
Conservative if parital, no instability or cannot have surgery

Operate on sportsmen
If multiple (and therefore compulsary)
Joint instability
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9
Q

What are the layers to a tendon?

A

Collagen bundles covered by endotenon
Make up fascicles covered by paratenon
Make up tendon covered by epitenon

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10
Q

Where are teh blood vessels in a tendon located?

A

In paratenon

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11
Q

How are tendons connected to their sheath?

A

By vinicula

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12
Q

What do the tendon sheaths contain?

A

A synovial lining + fluid for lubrication

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13
Q

What is the function of a tendon?

A

Flexible and very strong tension to allow for movement

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14
Q

What does immobility lead to?

A

Reduced water content
Reduced glycosaminoglycan concentration
Reduced strength

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15
Q

What are the types of tendon injury?

A
degeneration
	inflammation
	enthesiopathy
	traction apophysitis
	avulsion  bone fragment  *
	tear - intrasubstance (rupture) *
	tear - musculotendinous junction
	laceration/ incision
	crush / ischaemia / attrition
nodules
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16
Q

What is tendon degeneration?

A

Intrasubstance mucoid degneration
May be swollen, painful tender
Maybe asymptomatic

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17
Q

What are the symptoms of tendon inflammation?

A
Swollen
Tender
Hot
Red
Positive Finklestein test
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18
Q

What tendons are likely to become inflamed?

A

EPB
APL

Tendons through common tendon sheath at radial aspect of wrist

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19
Q

What is enthesiopathy?

A

Inflmmation at insertion to bone

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20
Q

Where is enthesiopathy likely to take place in a muscle?

A

The muscle origin rather than tendon insertion

Lateral humeral epicondylitis is a common example

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21
Q

What is traction apophysitis?

A

Where excessive pull by a large tenson causes damage to unfused apophysis
Recurrent load leading to inflammation

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22
Q

Who is likely to get traction apophysitis?

A

Adolescent active boys

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23
Q

What are some examples of traction apophysitis?

A

Osgood-Schlatter’s disease
Sever’s disease
Sinding Larsen’s disease

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24
Q

What is avulsion?

A

Where a structure is forcibly detached from it’s nomral point of insertion
I.e bone/ligament detachment leaving a fragment

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25
How do you treat avulsion
Conservative - limited application | Operative - reattachment /fixation
26
What is an intrasubstance tendon rupture?
Where the tendon ruptures | Happens when load exceeds failure strength
27
What are the signs in an achilles tendon rupture?
Positive simmonds test (squeeze test) | Palpable tendon gap
28
What is a musculotendinous junction tear?
Where the joint between the tendon and its muscle tears | Often partial
29
How do you treat tendon ruptures?
``` Conservative - splint/cast Mobilise Operative - ends cannot be opposed High risk of rereupture High activity ```
30
How do you treat lacerations of tendons?
Repair surgically and quickly | More common in young adults and men
31
What is the structure of a nerve?
Axons, coated in endoneurium, bundled into fascicles which are bundled into form a nerve Fasciles covered in Perineurium Epinerium for nerve
32
What is the speed of an Aa neurone?
60-100m/s
33
What is the function of an Aa neurone?
Large motor axons | Muscle stretch + tension seconsry axons
34
What is the speed of Ab neurones?
30-60m/s
35
What is the function of an Ab neurone?
Touch Pressure Vibration Prioprioception
36
What is the function of an Ay neurone?
Gamma efferent motor neruones
37
What is the speed of an Ay neurone?
15-30m/s
38
What is the function of an Ad neurone?
Sharp pain Light touch Temperature
39
What is the speed of an Ad neurone?
10-15m/s
40
What is the function of a B neurone?
Sympathetic preganglionic motor neurones
41
What is the speed of a B neurone?
3-10m/s
42
What is the speed of a C neurone?
<1.5m/s
43
What is the function of a C neurone?
Dull, sching or burning pain | Temperature sensation
44
What are teh types of periheral nerve injury?
Compression | Trauma (direct or indirect)
45
What are some examples of compression injuries?
Entrapment "Classical conditions" Carpal tuinnel syndrome (median nerve at wrist) Sciatic (spinal root by intervertebral disc) Mortons neuroma (digital nerve in 2nd/3rd webspace of foot)
46
What are the three types of trauma injury?
Neurapraxia Axontmesis Neurotmesis
47
What is neurpraxia?
A reversible conduction block caused by stretching or bruising There is local ischaemia and demyelination Good prognosis
48
What is axonotmesis?
Disruption of axons but endoneurium intact | Often due to being stretched, crushed or direct blow
49
What is the prognosis of axontmesis?
Okay - sensory often recover better than motor | May not go back to normal
50
What follows axonotmesis?
Wallerian degeneration
51
What is neurotmesis?
A complete nerve division, often caused by laceration or avulsion Endoneural tubes disrupted
52
What is the prognosis of neurotmesis?
No recovery unless repaired (graft/suture) Even under repair "miswiring" common Prognosis poor
53
What is a closed nerve injury?
Associated with nerve injuries in continuity (neuroprains/axontmesis) Spontaneous recover possible
54
When is surgery indicated in a closed nerve injury?
After 3 months if no recovery identified
55
What is an open nerve injury?
Frequently nerve division (often knife etc) | Distal portion dies (wallerian degneration)
56
How do you treat an open nerve injury?
Early surgery
57
What are the clinical features of a nerve injury?
Dsysaethesia (in sensory neurones) In motor - paresis/paralysis + wasting Dry skin due to no sweat gands Reflexes - diminished or absent
58
How do nerve injuries heal?
Distal nerve dies under wallerian degeneration Myelin sheath degrades Proximal axonal budding occurs after 4 days Regeneration at 1mm/day Pain is first modality to return
59
What is the prognosis for recovery from a nerve injury?
Dependant on if pure or mixed | How distal the lesion is (further the better)
60
What is Tinels sign?
Tap over site of nerve | Paraesthesia felt as distially as nerve recovered
61
When would you do a direct nerve repair?
In laceration No loss of nerve tissue Bundle repair
62
When would you use a nerve graft?
In nerve loss Or late repair Use sural nerve often
63
What is the rule of 3?
Immediate surgery within 3 days for sharp/clean injuries Early surgery within 3 weeks for blunt injuries Delayed (3 months) surgery for closed injury
64
What are the differences between cortical and cancellous bone?
Cortical bone found in diabpysis of bone Resists bending + torsion Circumfrentially laid Less biologically active Cancellous Found in metaphysis of bone, resists compression Site of longitudinal growth Biologically active
65
What is the diaphysis?
The shaft of a bone
66
What is the metaphysis and epipphysis?
Metamysis is flare at end of shaft | Epiphysis is on the joint side of physis
67
Where is the medullary canal found?
In the central cavity of the bone
68
What is a fracture?
Break in continuity of bone | Could be crack, break, split, crumpling or buckle
69
What can lead to a fracture (the bone failing)?
High energy transfer in normal bones Repetive stress in normal bones (stress #) Low energy in abnormal bones (osteoporosis, ostemalacia etc)
70
What happens to the bone in a fracture?
``` Mechanical + structural failure of bone Disruption of blood supply Regenerative process (no scar) ```
71
What are the four stages to fracture repair?
Inflammation Soft callous stage Hard callous stage Bone remodelling
72
What happens in the inflammation stage of fracture healing?
``` Begins immediately after # Forms haematoma and fibrin clot Lots of blood cells and by products f cell death Angiogensis starts if hypoxic Osteogenic induction of cells ```
73
How might we help the inflammation stage of fracture healing?
NSAIDs | Treat aemotoma in open fractures with surgery
74
What is the soft callus stage of fracture healing?
Begins when pain/swelling subside Lasts until bony fragments united by fibrous tissue/cartilage Some stability of fracture Continued increase in vascularity
75
How might we assits the soft callus stage of fracture healing?
Replace cartilage with demineralised bone matrix | Use bone graft
76
What is the hard callus stage of fracture healing?
Conversion of cartilage to woven bone Typical in long bone fracture - Increased rigidity although obvious callus
77
What is the bone remodelling stage of fracture healing?
Conversion of woven bone into lamellar bone Medullary canal reconstituted Bone responds to loading characteristics
78
What ca cause delayed union?
``` High energy union Distraction (increased osteogenic jumping) Instability Infection Steroids Immune suppresants Smoking Warfarin NSAIDs Ciprofloxacin ```
79
What is non-union?
Failure for fracture to heal
80
What can cause non-union?
``` failure calcification of fibrocartilage instability -excessive osteoclasis abundant callus formation pain + tenderness persistent fracture line sclerosis ```
81
What is an open fracture?
Direct communication between external environent and fracture
82
Why are open fractures significant?
Increased infection rate Soft tissue complications common Higher energy injury Long term morbidity
83
What are the types of open fracture?
type 1 - clean and simple, <1cm Type 2 - wound 1cm+ with soft tissue damage, simple fracture pattern Type 3 - extensive soft tissue damage, complex fracture pattern
84
What are the features of a type 3 open fracture?
High energy wound 10cm + often Extensive soft tissue damage
85
What are the subtypes of type 3 open fracture?
A - adequate periosteal coverage (not grossly contaminated) B - tisse loss requiring soft-tissue coverage procedure (graft etc) - extensive muscle damage C- vascular injury needing repair - neurovascular complication
86
What are the tibial fracture patterns?
Transverse/short oblique tibial fractures with fibular fractures Tibial fractures with communication with fibular fractures Segmental tibial fractures Fracutes with bone loss (either extrusion or debridement)
87
What are soft tissue injury patterns in a tibial fracture?
skin loss that tension free closure not possible Degloving Injury to muscles requiring excision via wound extensions Injury to 1+ major arteries in leg
88
How do you manage a complex open fracture?
Full advance trauma life support assesment + treatment Tetanus + antibiotic prophylaxis Repeated neurovascular status examination Wounds only handled to remove gross contamination
89
What are the indications for surgery?
``` Polytraumatise patient Marine/farmyard environment Gross contamination Neurovascular compromise Compartment syndrome ```
90
When debriding and fixing (surgery) what is looked for?
``` 4 Cs Colour Contraction Consistency Capacity to bleed ```
91
Who deals with skin coverage issues?
Plastic surgeons | Grafting
92
When is amputation considered?
Insensate limb/foot Irretrivable soft tissue or bony damage Other life threatening issues dual constultant decision
93
What is a dislocation?
Complete joint disruption
94
What is subluxation?
Partial dislocation (not fully outside joint)
95
How do you diagnose dislocation?
Clinically + radiological | Associated injuries - neurovasculat damage, soft tissue/msk damage
96
How do you treat dislocation
Relocation | Surgery if required
97
What dislocations can occur at the shoulder?
Anterior - squared off | Posterior - locked in internal rotation
98
What dislocations can happen at the elbow
Posterior - olecranon prominent posteriorly
99
What dislocations can happen at the hip?
Posterior - Leg short, flexed Internal rotation Adduction
100
What dislocations can occur at the knee?
Anteroposteriorly | Loss of normal contour, extended
101
What dislocations happen at ankle?
Lateral most common - externally rotated | Prominent medial malleolus
102
What locations occur at subtalar joint?
Lateral most common - displaced calcis (heel)