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Flashcards in Myocardial Infarction Deck (10)

What is a STEMI?

A myocardial infarction that illustrates ST elevation on an ECG


What is a NSTEMI?

A myocardial infarction that doesn't illustrate ST elevation on an ECG


What is an unstable angina?

Where there is partial occlusion of a coronary artery that leads to ischaemia that causes pain at rest


What causes a STEMI?

There is a rupture of a coronary plaque which leads to an occlusive thrombus (completely blocking a blood vessel) leading to large amount of ischaemia


What is ST elevation in myocardial infarction indicative of?

This indicates ischaemia


What are Q waves in myocardial infarction indicative of?

Infarction, irreversible myocardial death.


What are the clinical signs and symptoms of acute myocardial infarction?

As a result of ischaemic myocardial injury: chest pain (angina), a 4th heart sound, low grade fever, leukocytosis and raised CRP and troponin I and T release

As a result of autonomic disturbance: tachycardia, sweating and vomiting


What drugs may be given post-MI as a form of secondary prevention?

• Aspirin
• Ticagrelor (platelet aggregation inhibitor)
• Statin
• Beta-blocker
• ACE inhibitors


What are the treatments for NSTEMI?

Anti-coagulants, vasodilators and antiplatelet drugs.


How does fondaparinux prevent coagulation?

By inhibiting factor Xa (prevents prothrombin to thrombin conversion, and therefore prevents fibrin formation to form a stable clot)