NBS Microbiology- Immunology Flashcards
(99 cards)
1
Q
Which of the following is a phagocytic cell of the immune system? A. Basophil B. Mast cell C. Eosinophils D. Neutrophil
A
Neutrophil
- 3 main phagocytic cells are monocytes, macrophages and neutrophils
2
Q
Which cells would degranulate in response to an allergy? A. Basophil B. Mast cell C. Eosinophils D. Neutrophil
A
mast cells
3
Q
Which cell acts as a antigen presenting cell to T cells? A. Basophil B. Macrophage C. Neutrophil D. IL-6
A
Macrophage
4
Q
Which of the following can inactivate the pathogen? A. Macrophage B. Neutrophil C. NK cell D. Basophil
A
NK cell
5
Q
How many types of T cells are there?
A. 1
B. 3
C. 2
A
3
6
Q
Which of the following triggers target cells to commit suicide? A. Regulatory T cells B. Helper T cells C. Killer T cells D. Macrophages
A
Killer T cells
7
Q
This deals with antigen recognition and regulation; it also secretes a protein molecule (cytokine)? A. Regulatory T cells B. Helper T cells C. Killer T cells D. NK cell
A
Helper T cell
8
Q
Histocompatibility complex protein 1 would be scanned for what is inside by \_\_\_\_\_\_\_\_? A. Regulatory T cells B. Helper T cells C. Killer T cells D. NK cell
A
Killer T cell
9
Q
Histocompatibility complex protein 2 would be scanned for whats on the outside by\_\_\_\_\_\_\_? A. Regulatory T cells B. Helper T cells C. Killer T cells D. NK cell
A
Helper T cells
10
Q
An Antibody binds to the part of the antigen called the \_\_\_\_\_\_\_\_? A. Fragment B. Complex zone C. Epitope D. Cytokine
A
Epitope
11
Q
Which cells would produce cytokines and help to activate Helper T and Cytotoxic T cells? A. Dendritic cell B. Macrophage C. Neutrophil D. Mast cells
A
Macrophage
12
Q
Which of the following presents the antigen for T cells to see? A. Mast cell B. IgE C. Neutrophil D. Histocompatibility complex protein
A
Histocompatibility complex protein
13
Q
T/F: An Antibody killed the antigen
A
False
it simply tags it for death aka the kiss of death
14
Q
How many proteins are a part of the complement system? A. 20 B. 15 C. 21 D. 25
A
20
15
Q
Where are the proteins of the complement system made? A. Kidney B. Liver C. Adrenal Gland D. Heart
A
Liver
16
Q
T/F: The complement system is slow
A
False
its super duper fast
17
Q
Which of the following is antibody independent? A. Lectin activation pathway B. Classical pathway C. Alternative pathway D. Type 1 hypersensitivity
A
Alternative pathway
18
Q
During the lectin activation pathway \_\_\_\_\_\_\_binds to lectin and lectin binds to \_\_\_\_\_\_\_\_ on the pathogen. A. Maltose, Lipid molecule B. Maltose, Carbohydrate molecule C. Mannose, Carbohydrate molecule D. Glucose, Carbohydrate molecule
A
C
mannose, Carb molecule on pathogen
19
Q
Which of the following depends on an antibody for activation? A. Lectin activation pathway B. Classical pathway C. Alternative pathway D. Type 2 hypersensitivity
A
Classical pathway
20
Q
If you were dealing with the process of neutralizing antibodies, you most likely are: A. reducing the antigen B. oxidizing the antigen C. killing the antigen D. eating the antigen
A
oxidizing the antigen
this is your prepare to EAT stage
21
Q
The lectin activation pathway triggers inflammation after binding to the carbohydrate molecule on the antigen. This chemotactically attracts \_\_\_\_\_\_\_ to infection. A. Helper T cells B. mast cells C. Phagocytes D. Basophils
A
Phagocytes
22
Q
The lectin pathway signals B-lymphocytes causing lysis of gram ________ bacteria and foreign epitopes.
A. Negative
B. Positive
A
Negative
23
Q
Which type of hypersensitivity would be antibody mediated? A. Type 3 B. Type 4 C. Type 1 D. Type 2
A
Type 2
I AM IT
24
Q
IgE would be the main responding antibody to which of the following hypersensitivities? A. Type 3 B. Type 4 C. Type 1 D. Type 2
A
Type 1
Type 4 also but not as prevalent, bc type 4 is delayed
25
```
Type 2 Hypersensitivity would be associated with:
A. IgA and IgM
B. IgG
C. IgE and IgA
D. IgG and IgM
```
D
| IgG and IgM
26
```
Type 3 Hypersensitivity would be associated with:
A. IgA and IgM
B. IgG
C. IgE and IgA
D. IgG and IgM
```
IgG
27
```
Which hypersensitivity would you find myanstania gravis and pernicious anemia occurring?
A. Type 3
B. Type 4
C. Type 1
D. Type 2
```
Type 2
28
```
Which hypersensitivity would involve a rejection of a tissue graft?
A. Type 2
B. Type 4
C. Type 3
D. Type 1
```
Type 4
it may take a while (delayed) to reject it
29
```
Which hypersensitivity is immune complex mediated?
A. Type 3
B. Type 4
C. Type 1
D. Type 2
```
Type 3
30
```
Which hypersensitivity would be T cell mediated?
A. Type 3
B. Type 4
C. Type 1
D. Type 2
```
Type 4
31
```
If your child was diagnosed with systemic lupus erythematosus you would expect which of the following:
A. Antibody mediated hypersensitivity
B. Immediate hypersensitivity
C. Immune complex hypersensitivity
D. T cell mediated hypersensitivity
```
Immune complex hypersensitivity
aka Type 3
32
```
You have a patient come in with rheumatoid arthritis, this is an example of:
A. Antibody mediated hypersensitivity
B. Immediate hypersensitivity
C. Immune complex hypersensitivity
D. T cell mediated hypersensitivity
```
Immune Complex hypersensitivity
aka Type 3
33
```
Basophils and mast cells can be associated with:
A. Antibody mediated hypersensitivity
B. Immediate hypersensitivity
C. Immune complex hypersensitivity
D. T cell mediated hypersensitivity
```
immediate hypersensitivity
type 1
34
```
Which of the following could be associated with Immune Complex hypersensitivity?
A. Dermatitis
B. Anaphylaxis
C. Blood group incompatibility
D. Rheumatic fever
```
Rheumatic fever
35
```
SARS had an outbreak in what country in 2002?
A. Chile
B. United States
C. Africa
D. Chine
```
China
36
```
The Avian flu (bird flu) broke out in ASIA in what year?
A. 2003
B. 2004
C. 2000
D. 2001
```
2003
37
```
As of 2013, which of the following was named the most common foodborne disease?
A. Hantavirus
B. Tuberculosis
C. Norovirus
D. West Nile virus
```
Norovirus
38
```
As of 2013, what is the 2nd most common foodborne disease?
A. Salmonella
B. Rotavirus
C. Norovirus
D. Pertusis
```
Samonella
39
```
_________ is caused by proteins from mold or plant spores.
A. Asthma
B. SLE
C. Rheumatic fever
D. Hay fever
```
Hay fever
40
```
Allergic individuals who produce more IgE antibodies are referred to as:
A. Atopic
B. Ectopic
C. Mellitus
D. Recipients
```
Atopic
41
```
What is caused by dust mites, cockroaches, rodents and household pets?
A. Asthma
B. Myasthenia Gravis
C. Rheumatic fever
D. Hay fever
```
Asthma
42
```
Which of the following would attach to IgE antibodies?
A. Dendritic cells
B. Eosinophils
C. Basophils
D. Monocytes
```
Basophils
43
```
These are involved with chronic allergic responses:
A. Mast cells
B. Eosinophils
C. Basophils
D. Monocytes
```
Eosinophils
44
```
How long will IgE live in the blood?
A. several weeks
B. 1 week
C. 1 day
D. 1 year
```
1 day
45
```
How long wtih IgE live after it has been attaching to a Mast cell?
A. several weeks
B. 1 week
C. 1 day
D. 1 year
```
several weeks
46
T/F: Being more susceptible to allergies can be hereditary
True
47
```
Which autoimmune disease would involve the myoneural junction causing double vision or a face drooping appearance?
A. SLE
B. Multiple Sclerosis
C. Insulin-dependent diabetes mellitus
D. Myasthenia gravis
```
D
| Myasthenia Gravis
48
```
Myasthenia gravis deals with self-reactive antibodies that bind to receptors for _________?
A. Sodium
B. Ca++
C. Acetylcholine
D. Potassium
```
Acetylchloine
49
```
Which of the following is NOT an autoimmune disease?
A. Multiple Sclerosis
B. Systemic Lupus Erythematosus
C. DiGeorge Syndrome
D. Canale- Smith Syndrome
E. Myasthenia Gravis
```
DiGeorge syndrome
*its an immunodeficiency
50
```
Which antibodies are most commonly found with rheumatoid arthritis?
A. IgE and IgA
B. IgA and IgG
C. IgM and IgG
D. IgA and IgM
```
IgM and IgG
51
What do the antibodies in rheumatoid arthritis activate?
Macrophages
52
Which of the following best describes Canale-smith syndrome:
A. Organ specific immune disease targeting B cells
B. Destruction of the myelin sheath
C. Repeatedly stimulated lymphocytes and swollen nodes
D. Inflammation of the lungs, arthritis, kidney damage
C
Canale- Smith lymph is swollll
53
Which of the following best describes Multiple Sclerosis:
A. Organ specific immune disease targeting B cells
B. Destruction of the myelin sheath
C. Repeatedly stimulated lymphocytes and swollen nodes
D. Inflammation of the lungs, arthritis, kidney damage
B
| Destruction of the myelin sheath
54
Which of the following best describes Systemic Lupus Erythematosus?
A. Organ specific immune disease targeting B cells
B. Destruction of the myelin sheath
C. Repeatedly stimulated lymphocytes and swollen nodes
D. Inflammation of the lungs, arthritis, kidney damage
D
| Inflammation of the lungs, arthritis and kidney damage
55
```
Red facial rash or a malar butterfly rash is seen with which disease?
A. Rhematoid Arthritis
B. DiGeorge Syndrome
C. Systemic Lupus Erythematosus
D. Myasthenia Gravis
```
C
| SLE
56
```
This disease is caused by the breakdown of B and T cells that make IgG antibodies?
A. Systemic Lupus Erythematosus
B. DiGeorge Syndrome
C. Canale- Smith Syndrome
D. Myasthenia Gravis
```
A
| SLE
57
Multiple Scleosis effects primarily the ________?
A. CNS
B. PNS
CNS
58
```
This disease deals with self active T cells that can cross the blood brain barrier?
A. Systemic Lupus Erythematosus
B. DiGeorge Syndrome
C. Multiple Sclerosis
D. Myasthenia Gravis
```
Multiple Sclerosis
59
```
Which disease is more prevalent in women and can result in hair loss, paralysis and convulsions?
A. Rhematoid Arthritis
B. DiGeorge Syndrome
C. Systemic Lupus Erythematosus
D. Myasthenia Gravis
```
C
| SLE
60
Which disease deals with absent or severely reduced Thymic tissue and NO t cells?
A. AIDS
B. severe combined immunodeficiency syndrome
C. DiGeorge Syndrome
D. Karposi Sarcoma
DiGeorge Syndrome
61
You are born with no B or T cells. wWhat would you have?
A. AIDS
B. severe combined immunodeficiency syndrome
C. DiGeorge Syndrome
D. Karposi Sarcoma
B
Severe combines immunodeficiency syndrome
*REALLY BAD
62
```
Kaposi Sarcoma is associated with:
A. AIDS
B. severe combined immunodeficiency syndrome
C. DiGeorge Syndrome
D. SLE
```
AIDS
63
```
Which causative agent is associated with AID and HIV?
A. Pneumocystic Carnii
B. Polio virus
C. Norovirus
D. Coxsackie virus
```
A
| Pneumocystic Carnii
64
This is an example of a live attenuated virus?
A. Salk
B. Sabin
Sabin
65
Salk treated polio virus with formaldehyde to ______ the virus.
A. Enchance
B. Kill
Kill
salK - Kills
66
```
AIDS is caused by:
A. HIV-3
B. HPV-1
C. HIV-2
D HIV-1
```
D
| HIV-1
67
Noninfectious vaccines help to generate all of the following EXCEPT?
A. Memory B cells
B. Memory T helper cells
C. Memory T killer cells
Memory T Killer
68
```
What type of vaccine uses a weakened form of the microbe?
A. DNA Vaccine
B. Carrier Vaccine
C. Attenuated Vaccine
D. Non-infectious Vaccine
```
Attenuated Vaccine
69
Attenuated vaccines help to generate which of the following?
A. Memory B cells
B. Memory T helper cells
C. Memory T killer cells
Memory T killer
70
```
The vaccine for rubella, mumps, and measles is an example of:
A. DNA Vaccine
B. Carrier Vaccine
C. Attenuated Vaccine
D. Non-infectious Vaccine
```
Attenuated Vaccine
71
```
This type of vaccine is genetically engineered and introduces a single gene from pathogenic microbe into a virus?
A. DNA Vaccine
B. Carrier Vaccine
C. Attenuated Vaccine
D. Non-infectious Vaccine
```
Carrier Virus
72
T/F: Does a carrier vaccine cause disease
False
73
```
What type of vaccine is referred to as "the trojan horse"?
A. DNA Vaccine
B. Carrier Vaccine
C. Attenuated Vaccine
D. Non-infectious Vaccine
```
Carrier vaccine
74
```
Injecting a flu virus gene would describe which vaccine?
A. DNA Vaccine
B. Carrier Vaccine
C. Attenuated Vaccine
D. Non-infectious Vaccine
```
DNA Vaccine
75
This type of immunity is either attenuated or killed?
A. Active immunity
B. Passive-active immunity
C. Passive immunity
Active immunity
76
The type of immunity would occur naturally and can be found in mothers milk or via administered preformed antibodies in immune globulins?
A. Active immunity
B. Passive-active immunity
C. Passive immunity
Passive immunity is natural
77
Both immuno globulins (aka immunoglobulins, gamma globulins) & vaccines are associated with which type of immunity?
A. Active immunity
B. Passive-active immunity
C. Passive immunity
Passive-Active
78
```
Immunodiffusion testing is also called:
A. Immunoelectrophoresis
B. Ouchterlony test
C. Agglutination
D. Complement fixation test
```
B
| Ouchterolony test
79
```
This type of testing separates the molecule in order to look for a particular class of antibodies?
A. Immunoelectrophoresis
B. Ouchterlony test
C. Agglutination
D. Complement fixation test
```
A
| Immunoelectrophoresis
80
```
Multiple myeloma, AIDS and lyme disease (borrelia burgdorferi) can be detected using which type of test?
A. Complement Fixation test
B. ELISA
C. Western Blot
D. Immunoelectrophoresis
```
D
| Immunoelectrophoresis
81
```
Which of the following would involve antigen-antibody mixed, insoluble, huge complex formed?
A. Precipitates
B. Immunodiffusion
C. Agglutination
D. ELISA
```
Precipitates
82
```
This Test is used for influenze and mononucleosis, it clumps red blood cells and is NOT an antibody-antigen reaction:
A. Agglutination
B. Western Blot test
C. Viral Hemagglutination test
D. Viral Neutralizaton
```
C
| Viral Hemaggulination test
83
```
This test uses a dye an is commonly used to detect syphillis and mycobacterium TB:
A. Agglutination
B. Western Blot test
C. Complement Fixation test
D. Fluorescent Antibody test
```
D
| Fluorescent Antibody test
84
```
Western blot (aka imunnoblot) verifies the presence of antibodies against ________.
A. Fungal Antigens
B. HIV
C. Red Blood cells
D. Influenze
```
HIV
85
```
What Color will gram positive bacteria stain?
A. Red
B. Safranin
C. Purple
D. Blue
```
purple
86
```
This test detects the presence of specific antibodies in serum:
A. Agglutination
B. Western Blot test
C. Complement Fixation test
D. Fluorescent Antibody test
```
C
| Complement Fixation test
87
T/F: Rapid ELISAs are immunofiltration assays
True
88
```
Which of the following is actually an example of an electrophoresis test?
A. ELISA
B. Fluorescent antibody test
C. Western Blot
D. Viral Neutralization
```
C
| Western Blot
89
```
This is used in pregnancy testing and blood typing?
A. Agglutination
B. Western Blot test
C. Complement Fixation test
D. Fluorescent Antibody test
```
A
| Agglutination
90
```
When assessing things like meningitis, gonorrhea, salmonellosis, brucellosis and thyphoid fever you would be using which of the following:
A. Agglutination
B. Western Blot test
C. Complement Fixation test
D. Fluorescent Antibody test
```
A
| Agglutination
91
```
Which color would be seen in a counterstain?
A. Red
B. Safranin
C. Purple
D. Blue
```
Safranin
92
```
Which color would Gram negative stain?
A. Red
B. Safranin
C. Purple
D. Blue
```
Red
93
What type of rinse would be used as a decolorizer?
alcohol rinse
94
QUIZ: What would present antigen to T cell.....
Macrophage
95
QUIZ: Analphylaxis is seen in what hypersensitivity?
Type 1- immediate
96
QUIZ: You would find infections and dermatitis in which hypersensitivity?
Type 4- delayed (T cell mediated)
97
QUIZ: What type of cells inactive pathogens?
NK cells
98
QUIZ: This is the part of the antigen that the immune system recognizes...
Epitope
99
What is nike's logo?
Just do it
