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M3 Path B1 > Neoplasia 2: Genomic Instability > Flashcards

Neoplasia 2: Genomic Instability Flashcards

1
Q

Mismatch Repair

A

Microsatellite Instability

HNPCC (MSH2 and MLH1 gene) - have polyps, but are serrated adenomas

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2
Q

Nucleotide Excision Repair

A

Xeroderma Pigmentosa: Melanoma, Basal cell carcinoma, and Squamous cell carcinoma

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3
Q

Recombination Repair

A

Brca 1 and 2

If Brca 1 and 2 are mutated –> familial breast and ovarian tumors

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M3 Path B1 (29 decks)

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