Neoplasia 3: Chemical Initiatiors of Chemical Carcinogenesis Flashcards

1
Q

Direct

A

Cyclophosphamide, chlorambucil, busulfin, melphalan

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2
Q

Indirect: Polyacylic Aromatic Hydrocarbons

A

From: Cigs, smoked meat and fish

Effect: lung, bladder, and pancreatic cancers, small cell and squamous cell carcinoma (smoking)

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3
Q

Indirect: Aromatic Amines and Azo Dyes

A

Acetyl-aminoflorene and azy dyes –> hepatocellular carcinomas

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4
Q

Indirect: Beta-naphthylamine

A

Bladder cancer form aniline dye and rubber industry exposure

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