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M3 Path B1 > Neoplasia 3: Tumor Markers > Flashcards

Neoplasia 3: Tumor Markers Flashcards

1
Q

Tumor Markers

A

Done to detect enzymes and hormones secreted by tumors. They do not affect other organs, they either stay in blood or get excreted through urine.

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2
Q

Carcino-embryonic antigen

A

Stool assay to check CA levels

Colon, pancrease, stomach, and breast

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3
Q

Prostate-specific antegen (PSA)

A

Blood assay to see if elevated to SUSPECT (not dx) prostate cancer

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4
Q

Beta-hcg

A

Trophoblastic tumors (choriocarcinoma)

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5
Q

CA-125

A

Ovarian surface epithelial malignancies

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6
Q

alpha-fetoprotein (AFP)

A

Hepatocellular carcinomas

Germ cell tumors of testes or ovary

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7
Q

Catecholamines and metabolites

A

Pheochromocytoma

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8
Q

Immunoglobulins

A

Multiple myeloma and other gammopathies

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9
Q

CA 19-9

A

Colon, pancreatic cancer

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10
Q

TP53, APC, RAS mutants in stool and serum

A

Colon cancer

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11
Q

TP53, RAS mutants in stoom and serum

A

Pancreatic cancer

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M3 Path B1 (29 decks)

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