Flashcards in Neuro Deck (155)
What happens in posterior cord syndrome?
Loss of light touch, pressure, vibration and propioception from dermatomes below level of lesion but other sensory and motor functions remain intact
What occurs in large central cord lesion?
Loss of everything but sacral region can be spared.
Where are the second neruon cell bodies located in the DC/ML system?
Caudal medulla, axons dessucate as internal arcuate fibers
axons form medial leminiscus through rostral medulla pons ad midbrain
terminate in VPL
What occurs with lesion of medial leminiscus?
Loss of light touch, pressure, vibrationa nd propioception from dermatomes below lesion on cotnralateral side of body (medial medullary system)
The third neuron for DC/ML system are located where?
Cell body in VPL(ventral posterior lateral nucleus) of thalamus
axons pass through posterior limb of interal capsule
terminates in SI cortex
What is teh difference between VPL ad VPM in the THalamus?
VPL(ventral posterior lateral nuclues) sensation from body
VPM (Ventral posterior medial nucleus) sensation from body
Somatotopy occurs how in hte the thalamus?
most medial is face goes to foot as move laterally
How do axons from thalamus fan out?
As the corona radiata, fiibers from VPL and VPM pass to SI cortex
What occus with lesions of thalamus or SI cortex?
Loss of sensation from contralateral half of body
What brodmann area is responsible for limb movement?
What brodmann area is responsible for basic tactile information
What brodmanna rea is responsible for motion and direction of movment of objects?
What brodmann area is responsible for limb position, shapes of objects
What is the relationship between SI and SII cortex?
Located along upper border of Sylvian fissure and insular cortex, SI neurons project to SII cortex
Parietal association corticiess, what is a unimodal association cortex?
vision, auditory or somatosensory and a lesion causes agnosias (inability recognize object)
what is multimodal parietal association cortices?
combine sensation with motivation, attention, relevane
lesions lead to contralateral neglect
Anesthesia means what?
lack of sensation
lack of pain
hyperalgesia means what?
increased pain from normally painful stimulus
pain froma normally non-painful stimulus
hypoalgesia means what?
Decreased pain sensation
Pruritus means what?
nociceptive pain is what type of pain?
Pain resulting from tissue damage
well localized, throbbing quality
typically responds to NSAIDS
What type of pain is neuropathic pain?
Pain directly from damage to nerves
often has burning, lancinating, electrical qualty
resistant to NSAIDS and opoids
What sensation does the anterolateral system transmit?
Pain and temperature sensation to higher brain levels
What is the input to the anterolateral system?
noxious mechanical, thermal, or chemical stimulus to free nerve endings of Adelta or C fibers of nociceptors
Adelta fibers mediate what type of pain?
Mediate initial pain which is immediate, short-lasting, pricking quality
C fibers mediate what type of pain?
delayed, long lasting, burning quality
Where do central processors of nociceptors enter as part of teh anterolateral system?
Enter spinal cord dorsal horn, and synapse onto second order spinal neurons in lamina I/II. Some nociceptors synapse in lateral endge of spinal cord and a few near central canal.