Neuro-Ophthalmology: Neoplastic Chiasmal Disorders Flashcards
10 mm
pituitary tumor diameter that precedes supradiaphragmatic extension
diaphragma sella
structure immediately below the optic chiasm
inferonasal
fibers from this region of the retina are thought to contribute to the anterior knee of Wilbrand
superonasal
fibers from this region of the retina are most at risk from a pituitary adenoma
prefixed, central, postfixed
three chiasmal locations
80%
percentage of chiasms that are central
infertility, amenorrhea, galactorrhea
triad of symptoms caused by prolactin-secreting adenomas in women
gonadotropins
first hormone(s) to be lost in hypopituitarism
GH
second hormone(s) to be lost in hypopiuitarism
headache
symptom that occurs as a pituitary adenoma impinges on the diaphragma sella but may stop after it breaks through
chromophobe
type of adenoma (histologic) that is most likely to cause visual field defects
basophil
type of adenoma (histologic) that is least likely to cause visual field defects
dermatochalasis, tilted discs, optic nerve colobomas, nasal retinoschisis, nasal retinitis pigmentosa, functional visual loss
six nonchiasmal causes of bitemporal visual loss
color desaturation
early sign of chiasmal compression
hypointense
pituitary adenoma on T1
hyperintense
pituitary adenoma on T2
heterogeneous enhancement
pituitary adenoma on T1 with gadolinium contrast
enlargement or erosion of the sella
CT findings in pituitary adenoma
prolactin, FSH, LH, GH
routine endocrine studies in a patient suspected of having a pituitary adenoma (four)
bromocriptine, cabergoline
what two medical interventions for a prolactin-secreting pituitary adenoma may improve visual function in the space of hours?
trans-sphenoidal hypophysectomy
usual surgical treatment for pituitary adenoma
1 to 4 months
period of most rapid improvement of visual field defects following trans-sphenoidal hypophysectomy
hypopituitarism
craniopharyngioma presenting symptom in children
visual field defect
craniopharyngioma presenting symptom in adults
isointense
appearance of solid components of craniopharyngioma on T1 MRI
hyperintense
appearance of cystic components of craniopharyngioma on T1 MRI
radiotherapy
adjunctive treatment for pituitary adenomas, craniopharyngiomas, and meningiomas
sphenoidal ridge, olfactory groove, tuberculum sellae
three locations for intracranial meningiomas
fullness in the temporal fossa
classical finding seen in sphenoidal ridge meningiomas
third ventricle
the chiasm forms the anterior border of this structure
tuberculum sellae
anterior portion of the sella turcica
dorsum sellae
posterior portion of the sella turcica
prefixed
term for when the chiasm lies directly over the tuberculum sellae
postfixed
term for when the chiasm lies directly over the dorsum sellae
suprasellar cistern
term for space in which the chiasm resides
posterior
relative location of macular fibers in the chiasm
melanopsin
ganglion cells that project to the suprachiasmatic and supraoptic nuclei express this protein (retinohypothalamic tract)
asymmetric
characteristic pattern of visual acuity impairment in chiasmal disorders
poor depth perception, diplopia
in addition to field abnormalities, patients with chasmal syndromes should be asked about these symptoms
hemifield slide phenomenon
cause of diplopia in chiasmal syndromes