Objective 4 Flashcards

0
Q

What is sarcolemma?

A

Muscle cell plasma membrane

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1
Q

How long are the fibers of the skeletal muscle?

A

Each fiber is 10-100 um in diameter, and up to 100+ cm long (entire length of the muscle)

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2
Q

What is sarcoplasm?

A

Muscle cell cytoplasm

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3
Q

Describe skeletal muscle fiber cells

A

Multi-nucleated; many mitochondria

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4
Q

What do glycosomes within skeletal muscle fiber do?

A

They provide local glycogen storage

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5
Q

What is myoglobin?

A

a protein for local oxygen and iron storage

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6
Q

What are the specialized organelles of skeletal muscle fiber?

A

myofibrils, sarcoplasmic reticulum, T-tubules

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7
Q

Describe Myofibrils

A

They are densely packed, rod-like contractile elements

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8
Q

What percentage of muscle volume do myofibrils make up?

A

They make up ~80% of the muscle volume

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9
Q

Describe the arrangement of myofibrils within a fiber

A

The arrangement of myofibrils within a fiber is such that a perfectly aligned repeating series of dark A bands and light I bands is evident

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10
Q

What are myofibrils made up of?

A

many sarcomeres (smallest contractile unit of a muscle)

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11
Q

Describe Sarcoplasmic Reticulum (SR)

A

SR is an elaborate network of smooth endoplasmic reticulum that surrounds each myofibril
- Paired terminal cisternae form perpendicular cross channels

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12
Q

What is the function of Sarcoplasmic Reticulum (SR)?

A

SR functions in the regulation of intracellular calcium levels

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13
Q

How do the T tubules associate within the SR?

A

T tubules associate with the paired terminal cisternae

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14
Q

What are T tubules (Transverse Tubules)

A

T tubules are continuous within the sarcolemma

- the lumen of each T tubule is continuous with the extracellular space

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15
Q

How do T tubules penetrate into the interior?

A

T tubules penetrate into the interior at each A band-I band junction

16
Q

Describe how T tubules associate with paired terminal cisternae of the SR

A

T tubules associate with the paired terminal cisternae of the SR to form triads that encircle each sarcomere

17
Q

Describe the SR-T tubules relationships

A

T tubules serve to conduct impulses to the deepest regions of the muscle

18
Q

How do T tubule proteins act?

A

T tubule proteins act as voltage sensors
- At appropriate voltage, the voltage sensors signal for the release of Ca2+ from adjacent SR terminal cisternae voltage-gated channels.