Occular MOA Flashcards Preview

pharmacology II > Occular MOA > Flashcards

Flashcards in Occular MOA Deck (19):
1

Cyclosoporin/restasis

Dry eyes
T-cell inhibition
very dilute.05%

2

Visine

Red eyes
Class: occular astringent, anti redness
MOA: Vasoconstriction

3

Optivar

Conjunctivitis
Class: ocular antihistamine
MOA: HI blocker

4

Acular

Conjunctivitis: eye pain/swelling
Class: ocular NSAID
MOA: COX inhibition
NO increase for glaucoma or cataract like steroid

5

Polymyxin B/bacitracian

Bacterial conjunctivitis
Class: antibiotic
MOA: Protein synthesis inhibiton

6

Ara-A

Viral conjunctivitis
Antiviral for HSV
MOA: Inhibit viral DNA synthesis
Not for herpes zoster(shingles) doesn't go deep enough

7

Timolol

Glaucoma
Reduce aqueas humor production by blocking epi
MOA: Beta blocker
caution systemic absorption and lung issues

8

Xalatan

Glaucoma
Increase draining of aqueous humor
MOA: Prostaglandin receptor agonist ON
turn iris brown, increase eyelash growth

9

Pilocarpine

Glaucoma
increase draining by tightening cilary muscles.
MOA: cholinergic agonist: parasympathetic,

10

side effects of all the drugs

local irritation

11

Prostaglanding receptor agonist ON

xalantan: glaucoma

12

T cell inhibition

Cyclosporin/restasis: dry eyes

13

COX receptor blocker

Acular: ocular NSAID conjunctivitis ; does not cause glaucoma or conjunctivitis

14

vasoconstriction

Visine: red eyes: rebound vasodilation

15

Cholonergic agonist

Pilocarpine: glaucoma, draining

16

block viral dna synthesis

Ara A: HSV, not shingles/zoster: viral conjunctivitis

17

Antihistamine

Optivar: conjunctivitis

18

Bacterial protein synthesis

Polymyxin B/bacitracian: bacterial conjunctivitis

19

Beta blocker

Timolol: Glaucoma
Caution with fragile asthma etc