Opportunistic Infections Flashcards

1
Q

What is adalimumab

A

Humira is the trade name, it is an anti TNF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the categories of Immune deficiencies that you have to go through when prescribing anti inflammatory drugs or immuno suppressive drugs such as adalimumab

A
  1. T cell deficiency - like AIDS
  2. B cell deficiency - agammaglobulinemia
  3. Combined B and T cell deficiency - SCIDs
  4. Complement system defect
  5. Defect in the effectiveness of phagocytes - Chediak Higashi syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Those people who have C3 deficiency, what kind of diseases are they susceptible to

A

Steptococcal infections like pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What kind of therapy is there for those patient that have a suppressed immune system

A

HAART: Highly Active Anti-Retroviral Therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What kind of infections can you get with low CD4 count

A
  1. 500 - no infections, normal
  2. 200 to 500, increased risk of certain infections such as shingles, thrush, skin infections, lung infections, TB, diarheal infections like cryptosporadium that you can get from your dog
  3. Below 200, increased risk of Penumocystic pneumonia, chemoprophylaxis is given to prevent this
  4. Below 100, preventive treatment should begin like for toxoplasmosis, cryptococcus meningitis
  5. Below 50, increased risk to cytomegalovirus and MAI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly