Osteomyelitis and Ostosarcoama (Pead) Flashcards Preview

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Flashcards in Osteomyelitis and Ostosarcoama (Pead) Deck (20):
1

What type of iseae is osteomyelitis?

Infectious

2

Which types of diseae are common in bone and joints?

> Developmental
> Endocrine/metabolic
> Infectious (myelitis)
> Neoplastic (Osteosarc)
> Trauma (fx)
- vascular (rare)
- autoimmune (rare)
- degenerative (more joints)
- inflammatory (more joints)

3

Strict defintition of osteomyelitis? Used for?

> infection of corticol bone and medullary cavity
- used for any infection of bone

4

What i osteitis?

- term used by pahologists
- describes infection of cortex without involveent of red or yellow BM

5

What forms of osteomyelitis?

> Acute
- large or small animals
- sngle limb lamness, rapid onset, short duration
- often Hx of laceration or surgery
- clinical exam (heat, pain, swelling on palp, joint structures may be normal,febrile)
- differentiate joint from bone
> Chronic
- largies/smallies
- moderate intermitent lamenss days/weeks
- hx laceration or sugery
- clinical exam (MAY BE heat, pain, swelling, pain, discharge, sinus tract, pathological fx then becoems acute)

6

What is metabolism of bone like? How does this impact tx of an infection?

Poor - hard to fight infection
- not very cellular
- culture bugs and choose appropriate Abx

7

What does bone pathology always lead to?

BOTH
> bone loss (lysis)
> bone formation
(= same response to tumour/infection etc.)

8

Dxx for bone diseae

- Rads always
- Culture and sensitivity (when swabbing tracts, must get >2/3 up the tract before skin commensals not interfering)
- Biopsy for C+S
- radionucleatide scan (deermine high levels of bone activity)

9

Tx osteomyelitis

- early intervention BS
- change based on C+S
- conider local delivery (esp gentamycin)
- surgical debridement, immobilisation and lavage
- rehabilitation of entire limb

10

Ddx for osteomyelitis on rads?

Osteosarcoma

11

What tye of joint neoplasm may cause eroisin?

Synovial sarcoma - eating away at talus

12

Common presentation of osteosarcoma?

- old, large breed dog
- unilateral lamenss, chronic duration
- unesponsive to analgesia, excercise restriction
- pain on deep palpation of distal radius (common predilection site) and welling

13

Work up of potential osteosarcoma case

- clinical evaluation
- radiograph
- swab tracts
- Biopsy (Jamshidi, no. of planes but minimal skin incisions) definitive dx based on biopsy and culture
- staging and evaluation of prrognosis

14

Outline bone biopsy technique

- Jamshidi needle or Michelle trephine
- through centre of lesion (not margins)
- sample cortex and medulla
- multiple samples (same skin incision)
- cytology and cultulre
- ID landarks for pathologist (core v outside of lesion)

15

Are osteosarcomas common?

Dogs yes
- cats and horses v rare

16

Ddx osteosarcoma?

- feline TB
- calcinosis circumscripta

17

Decision making aspects of osteosarcoma tx?

- unremittengly painful if left aloone (analgesia wont do)
- must tx 1* successfully
- consider 2* spread (nearly all osteosarcs have micromets in the lung at time of dx)
- client communication (many people find skeletal tumour hard to understan implications)

18

Tx osteosarcoma? Prog?

- amputation (4mo)
- amputation + chemo (12-14mo)
- limb sparing + chemo (12-14)
- radiotx (palliative only)
- NSAIDs/bisphosphonates (pallliative only)
- euthanasia
> >talk to owners repeatedly!

19

What are the potential prsentations of osteosarcomas?

- lytic
- proliferative
- destructive

20

When can osteosarcoma and osteomyelitis affect animals?

Any age throughout its life (generally >1year)