Our Clues 15

Question 1

Location of GLUT 3

Answer 1

neuronal axons
dendrite
placenta
testes

Question 2

Location of GLUT 4

Answer 2

skeletal muscle
adipose
cardiac muscle

Question 3

Location of GLUT 5

Answer 3

= Fructose transporter

intestines
testes
sperm

Question 4

What are the catalase positive organisms?

Answer 4

Bordetella pertussis
H pylori
Pseudomonas
Listeria
Candida
Staphylococci
E coli
Nocardia
Serratia
Burkholderia cepacia

Question 5

What is the 2nd messenger of all hypothalamic hormones?
Except?

Answer 5

IP3-DAG

Except CRH, which is cAMP

Question 6

Drugs that bind to ergosterol

Answer 6

Antifungal
- Amphotericin B
IV
pokes holes in cells releasing K+
topical: Nystatin, Mycostatin
- Miconazole, Clotrimazole
topical
- Tolnaftate
powder
- Terbinafine
nail infection
inhibits mitosis

Question 7

Drugs that inhibit ergosterol synthesis

Answer 7

Antifungals
- Fluconazole
best CNS penetration
DOC for cryptococcus
- Itraconazole
- Voriconazole
best for aspergillosis
- Ketoconazole
inhibits p450
block 5-alpha-reductase